Endovascular clot retrieval (ECR)

Changed by Mark Thurston, 9 Dec 2017

Updates to Article Attributes

Body was changed:

Mechanical thrombectomy for acute ischaemic stroke is the endovascular retrieval of clots obstructing large intracranial vessel in acute ischemic stroke patients.

History

In 2015, multiple randomized controlled trials showed improved clinical outcome in patients with acute stroke due to large vessel occlusion undergoing thrombectomy compared to medical treatment alone.

Indications

  • Acute ischaemic stroke due to large vessel occlusion in the anterior circulation within 6 hours of symptom onset.
  • As of 2017, several trials are underway determining whether selected patients groups who fall outside of the 6 hour time window might also benefit from thrombectomy.

Contraindications

Procedure

Preprocedural evaluation

Non-contrast enhanced CT is used to exclude haemorrhage and CT angiography to determine large vessel occlusion. Alternatively, MRI and DSA may also demonstrate the occlusion. The role of advanced imaging such as CT perfusion to determine the infarct core and penumbra size is still uncertain.

Positioning/room set up
Equipment
  • Stentstent retrievers
  • Aspirationaspiration devices
  • Balloonballoon guiding catheter
  • Microcathetersmicrocatheters
Technique

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Postprocedural care

Complications

The overall complication rate is about 15%.1 Complications include:

  • Intracranialintracranial haemorrhage (intracerebral(parenchymal or subarachnoidalsubarachnoid)
  • Emboliemboli to new territories
  • Vesselvessel perforation
  • Arterialarterial dissection
  • Vasospasmvasospasm
  • Vascularvascular access site complications

Outcomes

The technical outcome is graded using the mTICI score. Thrombectomy is a highly effective treatment for stroke with a number needed to treat of 2.6 for the improved functional outcome. In a meta-analysis, 46% of patients treated with mechanical thrombectomy achieved functional independence (mRS 0–2 at 90 days) compared to 27% for best medical treatment.2

See also

  • -<li>Stent retrievers</li>
  • -<li>Aspiration devices</li>
  • -<li>Balloon guiding catheter</li>
  • -<li>Microcatheters</li>
  • +<li>stent retrievers</li>
  • +<li>aspiration devices</li>
  • +<li>balloon guiding catheter</li>
  • +<li>microcatheters</li>
  • -<li>Intracranial haemorrhage (intracerebral or subarachnoidal)</li>
  • -<li>Emboli to new territories</li>
  • -<li>Vessel perforation</li>
  • -<li>Arterial dissection</li>
  • -<li>Vasospasm</li>
  • -<li>Vascular access site complications</li>
  • +<li>intracranial haemorrhage (parenchymal or subarachnoid)</li>
  • +<li>emboli to new territories</li>
  • +<li>vessel perforation</li>
  • +<li>arterial dissection</li>
  • +<li>vasospasm</li>
  • +<li>vascular access site complications</li>

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