Ependymal rosettes (ependymoma)
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Ependymal rosettes correspond to a histologic architectural pattern that veryare characteristic of ependymomas, as tumour cells form structures similar to the lining of normal ventricles. They are characterised by a halo or spoke-wheel arrangement of tumour cells surrounding an empty central tubule lumen.
They should not be confused with the far more common perivascular pseudorosettes.
Differential diagnosis
In addition to perivascular pseudorosettes, an ependymal rosette should be differentiated from:
- Homer Wright rosette: central lumen filled with fiber-like processes
- Flexner-Wintersteiner rosette: central lumen contains small cytoplasmic extensions of the encircling cells
- pineocytomatous and neurocytic rosettes: generally larger and more irregular in contour
-<p><strong>Ependymal rosettes</strong> correspond to a histologic architectural pattern that very characteristic of <a href="/articles/ependymoma">ependymomas</a>, as tumour cells form structures similar to the lining of normal ventricles. They are characterised by a halo or spoke-wheel arrangement of tumour cells surrounding an empty central tubule lumen.</p><p>They should not be confused with the far more common <a href="/articles/perivascular-pseudorosettes-ependymoma">perivascular pseudorosettes</a>. </p><h4>Differential diagnosis</h4><p>In addition to perivascular pseudorosettes, an ependymal rosette should be differentiated from:</p><ul>- +<p><strong>Ependymal rosettes</strong> correspond to a histologic architectural pattern that are characteristic of <a href="/articles/ependymoma">ependymomas</a>, as tumour cells form structures similar to the lining of normal ventricles. They are characterised by a halo or spoke-wheel arrangement of tumour cells surrounding an empty central tubule lumen.</p><p>They should not be confused with the far more common <a href="/articles/perivascular-pseudorosettes-ependymoma">perivascular pseudorosettes</a>. </p><h4>Differential diagnosis</h4><p>In addition to perivascular pseudorosettes, an ependymal rosette should be differentiated from:</p><ul>
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