Homer Wright rosettes are differentiated tumour cells grouped around a central region containing neuropil (therefore its association with tumors of neuronal origin).
Examples of tumours where these can be seen include:
- medulloblastoma (the presence of Homer Wright rosettes in a posterior fossa tumour is nearly pathognomonic for medulloblastoma)
- primitive neuroectodermal tumors (PNETs)
- olfactory neuroblastoma
History and etymology
Homer Wright rosettes are named after James Homer Wright (1869–1928), Massachusetts (USA), developer of the Wright stain.
- 1. Wippold FJ, Perry A. Neuropathology for the neuroradiologist: rosettes and pseudorosettes. AJNR Am J Neuroradiol. 2006;27 (3): 488-92. Pubmed citation