Familial medullary thyroid carcinoma

Familial medullary thyroid carcinoma (FMTC) is a genetic disorder closely related multiple endocrine neoplasia type IIa (MEN2a) and multiple endocrine neoplasia type IIa (MEN2b). It is characterized by the development of medullary thyroid cancer.  

FMTC is the result of mutations in the RET (rearranged during transfection) proto-oncogene (10q11.2) and is inherited in an autosomal dominant fashion 1. Unlike other multiple endocrine neoplasia syndromes, FMTC exclusively involves the thyroid gland 1

Article information

rID: 59400
System: Head & Neck
Synonyms or Alternate Spellings:

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