Fetal warfarin syndrome
Updates to Synonym Attributes
Updates to Article Attributes
Title
was changed:
Fetal Warfarinwarfarin syndrome
Body
was changed:
Fetal warfarin syndrome (FWS) is a rare condition which can occur as a result of fetal exposure to maternal ingestion of Warfarinwarfarin during pregnancy.
Pathology
The increased risk is at ~6-9 weeks gestation.
Clinical features
Reported clinical features include:
Facial anomalies
Skeletal anomalies
- stippled
nonnon calcified epiphyses - shortened fingers: brachydactyly
- nail hypoplasia
- scoliosis
Central nervous system
- mental retardation
- seizures
- ventriculomegaly
- agensis of corpus callosum
- microcephaly
- microphthalmia
- congenital cataracts
Cardiovascular
Differential diagnosis
- some features (particulalrly
skeletalskeletal) can mimic that of chondrodysplasia punctata
-<p><strong>Fetal warfarin syndrome (FWS)</strong> is a rare condition which can as a result of fetal exposure to maternal ingestion of Warfarin during pregnancy.</p><h4>Pathology</h4><p>The increased risk is at ~6-9 weeks gestation.</p><h4>Clinical features</h4><p>Reported clinical features include:</p><h6>Facial anomalies</h6><ul>-<li><a href="/articles/nasal-bony-hypoplasia">nasal bony hypoplasia</a></li>- +<p><strong>Fetal warfarin syndrome (FWS)</strong> is a rare condition which can occur as a result of fetal exposure to maternal ingestion of warfarin during pregnancy.</p><h4>Pathology</h4><p>The increased risk is at ~6-9 weeks gestation.</p><h4>Clinical features</h4><p>Reported clinical features include:</p><h6>Facial anomalies</h6><ul>
- +<li><a href="/articles/nasal-bony-hypoplasia">nasal bone hypoplasia</a></li>
-<li>stippled non calcified epiphyses</li>- +<li>stippled non calcified epiphyses</li>
- +<li><a title="Fetal ventriculomegaly" href="/articles/fetal-ventriculomegaly">ventriculomegaly</a></li>
- +<li><a title="Agenesis of the corpus callosum" href="/articles/dysgenesis-of-the-corpus-callosum">agensis of corpus callosum</a></li>
-</ul><h6>Cardiovascular</h6><ul><li><a href="/articles/congenital-cardiovascular-anomalies">congenital cardiac anomalies</a></li></ul><h4>Differential diagnosis</h4><ul><li>some features (particulalrly skeletal) can mimic that of <a href="/articles/chondrodysplasia-punctata">chondrodysplasia punctata</a>- +</ul><h6>Cardiovascular</h6><ul><li><a href="/articles/congenital-cardiovascular-anomalies">congenital cardiac anomalies</a></li></ul><h4>Differential diagnosis</h4><ul><li>some features (particulalrly skeletal) can mimic that of <a href="/articles/chondrodysplasia-punctata">chondrodysplasia punctata</a>
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