Florid reactive periostitis

Last revised by Arlene Campos on 12 Jan 2024

Florid reactive periostitis is a rare benign lesion, included in a group of reactive bone and soft tissue lesions that create a frequent diagnostic problem.

Florid reactive periostitis occurring often in the 2nd  and 3rd  decade of life with a male to female ratio of 1 to 1.5, even though the affected age group stated in the literature varied from 5 to 70 years 1-4.

The lesion is usually formed in the hand phalanges, mainly in the proximal phalanx, and is characterized by an excessive osteoblast formation in a fibrous proliferative stroma arising at the level of the finger periosteum.

Soft tissue expansion and periosteal bone new bone formation that may seem as lamellar or mature bone. The cortex is typically intact.

Differential diagnoses include 5

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