Granulomatosis with polyangiitis (upper respiratory tract manifestations)

Dr Henry Knipe et al.

The upper respiratory tract manifestations of granulomatosis with polyangiitis (GPA), which was formerly known as Wegener granulomatosis, are common and affect most patients.

The majority of patients of GPA have upper respiratory tract involvement, most commonly presenting with rhinitis and epistaxis 1,3.

GPA manifests in the upper respiratory tract with 1-3:

  • sinusitis/mastoiditis/otitis
  • sinonasal mucosal ulcers
  • bone deformities, e.g. nasal septal perforation, nasal saddle deformity
  • subglottic stenosis
CT

Possible considerations include:


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Article Information

rID: 43203
System: Head & Neck
Section: Pathology
Synonyms or Alternate Spellings:
  • Upper respiratory tract manifestations of Wegener granulomatosis
  • Upper respiratory tract manifestations of granulomatosis with polyangiitis (GPA)

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    Case 3: with sinus and nasal septal involvement
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