Inflammatory myofibroblastic tumor

Changed by Mohammad Taghi Niknejad, 11 Jan 2024
Disclosures - updated 29 Dec 2023: Nothing to disclose

Updates to Article Attributes

Body was changed:

Inflammatory myofibroblastic tumours (IMT), also known as plasma cell granulomas, are rare neoplasms that have a diverse spectrum of biological behaviour. 

Terminology

These tumours were previously referred to as inflammatory pseudotumours.  

Epidemiology

They can occur at any age and there is currently no recognised gender predilection.

Pathology

Composed of spindle cells (key feature) with a variable infiltrate of inflammatory cells and fibrous tissue. They can occur at numerous sites:

  • more common 3

    • lung

    • head and neck

    • mesentery

    • gastrointestinal tract

    • retroperitoneum

    • musculoskeletal system

  • less common 

    • liver 8 

    • spleen 10

    • urogenital tract 6 

Radiographic features

Radiological features of inflammatory myofibroblastic tumours suggest malignant neoplasms, whereas they are not and these lesions are underdiagnosed entities 11.

Imaging characteristics depend on the organ of involvement:

  • -<li><p><a href="/articles/inflammatory-myofibroblastic-tumour-of-the-liver" title="Inflammatory myofibroblastic tumour of the liver">inflammatory myofibroblastic tumour of the liver</a></p></li>
  • -<li><p><a href="/articles/inflammatory-myofibroblastic-tumour-of-the-gastrointestinal-tract" title="Inflammatory myofibroblastic tumour of the gastrointestinal tract">inflammatory myofibroblastic tumour of the gastrointestinal tract</a></p></li>
  • -<li><p><a href="/articles/inflammatory-myofibroblastic-tumour-of-the-mesentery" title="Inflammatory myofibroblastic tumour of the mesentery">inflammatory myofibroblastic tumour of the mesentery</a></p></li>
  • -<li><p><a href="/articles/inflammatory-myofibroblastic-tumour-of-the-urogenital-system" title="Inflammatory myofibroblastic tumour of the urogenital system">inflammatory myofibroblastic tumour of the urogenital system</a></p></li>
  • -<li><p><a href="/articles/inflammatory-myofibroblastic-tumour-of-the-head-and-neck" title="Inflammatory myofibroblastic tumour of the head and neck">inflammatory myofibroblastic tumour of the head and neck</a></p></li>
  • -<li><p><a href="/articles/inflammatory-myofibroblastic-tumour-of-the-musculoskeletal-system" title="Inflammatory myofibroblastic tumour of the musculoskeletal system">inflammatory myofibroblastic tumour of the musculoskeletal system</a></p></li>
  • +<li><p><a href="/articles/inflammatory-myofibroblastic-tumours-of-the-liver-1" title="Inflammatory myofibroblastic tumour of the liver">inflammatory myofibroblastic tumour of the liver</a></p></li>
  • +<li><p><a href="/articles/inflammatory-myofibroblastic-tumours-of-the-gastrointestinal-tract-1" title="Inflammatory myofibroblastic tumour of the gastrointestinal tract">inflammatory myofibroblastic tumour of the gastrointestinal tract</a></p></li>
  • +<li><p><a href="/articles/inflammatory-myofibroblastic-tumours-of-the-mesentery-1" title="Inflammatory myofibroblastic tumour of the mesentery">inflammatory myofibroblastic tumour of the mesentery</a></p></li>
  • +<li><p><a href="/articles/inflammatory-myofibroblastic-tumours-of-the-urogenital-system-1" title="Inflammatory myofibroblastic tumour of the urogenital system">inflammatory myofibroblastic tumour of the urogenital system</a></p></li>
  • +<li><p><a href="/articles/inflammatory-myofibroblastic-tumours-of-the-head-and-neck-1" title="Inflammatory myofibroblastic tumour of the head and neck">inflammatory myofibroblastic tumour of the head and neck</a></p></li>
  • +<li><p><a href="/articles/inflammatory-myofibroblastic-tumours-of-the-musculoskeletal-system" title="Inflammatory myofibroblastic tumour of the musculoskeletal system">inflammatory myofibroblastic tumour of the musculoskeletal system</a></p></li>
Images Changes:

Image 4 CT (C+ portal venous phase) ( create )

Caption was added:
Case 4
Position was set to 4.

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