Inflammatory myofibroblastic tumor
Updates to Article Attributes
Inflammatory myofibroblastic tumours (IMT), also known as plasma cell granulomas, are rare neoplasms that have a diverse spectrum of biological behaviour.
Terminology
These tumours were previously referred to as inflammatory pseudotumours.
Epidemiology
They can occur at any age and there is currently no recognised gender predilection.
Pathology
Composed of spindle cells (key feature) with a variable infiltrate of inflammatory cells and fibrous tissue. They can occur at numerous sites:
-
more common 3
lung
head and neck
mesentery
gastrointestinal tract
retroperitoneum
musculoskeletal system
-
less common
liver 8
spleen 10
urogenital tract 6
Radiographic features
Radiological features of inflammatory myofibroblastic tumours suggest malignant neoplasms, whereas they are not and these lesions are underdiagnosed entities 11.
Imaging characteristics depend on the organ of involvement:
-<li><p><a href="/articles/inflammatory-myofibroblastic-tumour-of-the-liver" title="Inflammatory myofibroblastic tumour of the liver">inflammatory myofibroblastic tumour of the liver</a></p></li>-<li><p><a href="/articles/inflammatory-myofibroblastic-tumour-of-the-gastrointestinal-tract" title="Inflammatory myofibroblastic tumour of the gastrointestinal tract">inflammatory myofibroblastic tumour of the gastrointestinal tract</a></p></li>-<li><p><a href="/articles/inflammatory-myofibroblastic-tumour-of-the-mesentery" title="Inflammatory myofibroblastic tumour of the mesentery">inflammatory myofibroblastic tumour of the mesentery</a></p></li>-<li><p><a href="/articles/inflammatory-myofibroblastic-tumour-of-the-urogenital-system" title="Inflammatory myofibroblastic tumour of the urogenital system">inflammatory myofibroblastic tumour of the urogenital system</a></p></li>-<li><p><a href="/articles/inflammatory-myofibroblastic-tumour-of-the-head-and-neck" title="Inflammatory myofibroblastic tumour of the head and neck">inflammatory myofibroblastic tumour of the head and neck</a></p></li>-<li><p><a href="/articles/inflammatory-myofibroblastic-tumour-of-the-musculoskeletal-system" title="Inflammatory myofibroblastic tumour of the musculoskeletal system">inflammatory myofibroblastic tumour of the musculoskeletal system</a></p></li>- +<li><p><a href="/articles/inflammatory-myofibroblastic-tumours-of-the-liver-1" title="Inflammatory myofibroblastic tumour of the liver">inflammatory myofibroblastic tumour of the liver</a></p></li>
- +<li><p><a href="/articles/inflammatory-myofibroblastic-tumours-of-the-gastrointestinal-tract-1" title="Inflammatory myofibroblastic tumour of the gastrointestinal tract">inflammatory myofibroblastic tumour of the gastrointestinal tract</a></p></li>
- +<li><p><a href="/articles/inflammatory-myofibroblastic-tumours-of-the-mesentery-1" title="Inflammatory myofibroblastic tumour of the mesentery">inflammatory myofibroblastic tumour of the mesentery</a></p></li>
- +<li><p><a href="/articles/inflammatory-myofibroblastic-tumours-of-the-urogenital-system-1" title="Inflammatory myofibroblastic tumour of the urogenital system">inflammatory myofibroblastic tumour of the urogenital system</a></p></li>
- +<li><p><a href="/articles/inflammatory-myofibroblastic-tumours-of-the-head-and-neck-1" title="Inflammatory myofibroblastic tumour of the head and neck">inflammatory myofibroblastic tumour of the head and neck</a></p></li>
- +<li><p><a href="/articles/inflammatory-myofibroblastic-tumours-of-the-musculoskeletal-system" title="Inflammatory myofibroblastic tumour of the musculoskeletal system">inflammatory myofibroblastic tumour of the musculoskeletal system</a></p></li>