Intracranial neuroentric cyst

Dr Amir Rezaee et al.

Neurenteric cysts are developmental CNS lesions arising from endoderm. 

They result from incomplete resorption of the neurenteric canal, a temporary connection between yolk sac and amnion during early embryogenesis. Intracranial neuroentric cysts are extra axial and in 80% of cases are in posterior fossa anterior to pontomedullary junction and 20% in supratentorium adjacent to the frontal lobes. Intracranial neuroentric cysts are much less common than spinal neuroentric cysts.


Iso- to slightly hyper-attenuating compared to the CSF with no enhancement.


MRI is the modality of choice, and appearances depend on the variable protein content:

  • T1: iso to slightly hyperintense to CSF
  • T2: hyperintense to CSF
  • FLAIR: does not suppress 

Imaging differential considerations include:

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Article information

rID: 36532
Section: Pathology
Tags: refs, cases
Synonyms or Alternate Spellings:
  • Intracranial neuroentric cysts

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