Intrapleural space

Changed by Craig Hacking, 7 Feb 2019

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The intrapleural or pleural space is the fluid-filled space in between the parietal and visceral layers of the pleura. In normal conditions it contains only a small amount of serous pleural fluid.

Variant anatomy

Rarely there may be anomalous communication of the pleural spaces anteriorly. 

Related pathology

A pleural effusion is the pathological accumulation of pleural fluid, and when infected becomes an empyema

The pleural space can also be affected by a number of malignancies:

When air leaks into the pleural space, a life threatening pneumothorax may develop.

  • -<p>The <strong>intrapleural </strong>or<strong> pleural space</strong> is the fluid-filled space in between the parietal and visceral layers of the <a href="/articles/pleura">pleura</a>. In normal conditions it contains only a small amount of serous pleural fluid.</p><h4>Related pathology</h4><p>A <a href="/articles/pleural-effusion">pleural effusion</a> is the pathological accumulation of pleural fluid, and when infected becomes an <a title="Empyema" href="/articles/thoracic-empyema-1">empyema</a>. </p><p>The pleural space can also be affected by a number of malignancies:</p><ul>
  • -<li><a title="Pleural mesothelioma" href="/articles/mesothelioma">mesothelioma</a></li>
  • -<li><a title="Pleural metastases" href="/articles/pleural-metastases">pleural metastases</a></li>
  • -<li><a title="Pleural fibroma" href="/articles/pleural-fibroma">pleural fibroma</a></li>
  • -<li><a title="Pleural lymphoma" href="/articles/pleural-lymphoma">pleural lymphoma</a></li>
  • -</ul>
  • +<p>The <strong>intrapleural </strong>or<strong> pleural space</strong> is the fluid-filled space in between the parietal and visceral layers of the <a href="/articles/pleura">pleura</a>. In normal conditions it contains only a small amount of serous pleural fluid.</p><h4>Variant anatomy</h4><p>Rarely there may be anomalous communication of the pleural spaces anteriorly. </p><h4>Related pathology</h4><p>A <a href="/articles/pleural-effusion">pleural effusion</a> is the pathological accumulation of pleural fluid, and when infected becomes an <a href="/articles/thoracic-empyema-1">empyema</a>. </p><p>The pleural space can also be affected by a number of malignancies:</p><ul>
  • +<li><a href="/articles/mesothelioma">mesothelioma</a></li>
  • +<li><a href="/articles/pleural-metastases">pleural metastases</a></li>
  • +<li><a href="/articles/solitary-fibrous-tumour-of-the-pleura">pleural fibroma</a></li>
  • +<li><a href="/articles/pleural-lymphoma">pleural lymphoma</a></li>
  • +</ul><p>When air leaks into the pleural space, a life threatening <a title="Pneumothorax" href="/articles/pneumothorax">pneumothorax</a> may develop.</p>

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