Lung cancer (staging - IASLC 7th edition) (historical)
Updates to Article Attributes
Body
was changed:
Non-small cell lung cancer (NSCLC) staging can be accomplished both by the TNM system, or by the AJCC staging system.
For a general discussion of these tumours please refer to the article on non-small cell lung cancer (NSCLC).
TNM system
The current 7th edition NSCLC staging is as follows 4:
Primary tumour (T)
- Tx: malignant cells on cytology but no tumour found on bronchoscopy or imaging.
- Tis: carcinoma in situ
-
T1:
- T1a: smaller than 2 cm in longest dimension
- T1b: larger than 2 cm but smaller or equal to 3 cm
-
T2: >3 cm in size and >2 cm from carina, or visceral pleural involvement, or lobar atelectasis
- T2a: larger than 3 cm but smaller than 5 cm
- T2b: larger than 5 cm but smaller than 7 cm
-
T3:
- <2 cm from carina but not involving trachea or carina
- involvement of chest wall, diaphragm, mediastinal pleura or parietal pericardium, separate tumour nodule(s) in the same lobe
-
T4:
- involvement of the trachea, oesophagus, vertebra, great vessels or heart
- separate tumour nodules in the same lung but not in the same lobe
Nodal status (N)
- Nx: regional nodes cannot be assessed
- N0: no regional nodal metastases
- N1: ipsilateral peribronchial, hilar or intrapulmonary nodes
- N2: ipsilateral mediastinal or subcarinal nodes
- N3: contralateral nodal involvement ; ipsilateral or contralateral scalene or supraclavicular nodal involvement
Distant metastasis (M)
- Mx: distant metastases cannot be assessed
- M0: no distant metastases
-
M1: distant metastases present
- M1a: presence of a malignant pleural effusion, pleural dissemination, or pericardial disease, intrathoracic metastases (metastasis in opposite lung)
- M1b: extrathoracic metastases
AJCC staging system
-
stage 0
- TNM equivalent: carcinoma in stiu
- resectable: yes
-
stage I
- TNM equivalent: T1 or T2, N0, M0
- resectable: yes
- 5 year survival: 47%
-
stage IIa
- TNM equivalent: T1, N1, M0
- resectable: yes
-
stage IIb
- TNM equivalent: T2, N1, M0 or T3, N0, M0
- resectable: yes
- 5 year survival: 26%
-
stage IIIa
- TNM equivalent: T1 or 2, N2, M0 or T3, N1 or 2, M0
- resectable: yes
--------------- accepted cut off between resectable and non resectable ----------
-
stage IIIb
- TNM equivalent: T1, 2 or 3, N3, M0 or T4, N0, 1, 2 or 3, M0
- resectable: no
- 5 year survival: 8%
-
stage IV
- TNM equivalent: any T, any N with M1
- resectable: no
- 5 year survival: 2%
Histological grade
- grade 1: well differentiated
- grade 2: moderately differentiated
- grade 3: poorly differentiated
- grade 4: undifferentiated
See also
-</ul><h4>See also</h4><ul>-<li><a href="/articles/lung-cancer-3">bronchogenic carcinoma</a></li>-<li><a href="/articles/small-cell-lung-cancer-staging">small cell lung cancer staging</a></li>-<li><a href="/articles/lung-cancer-staging-iascl-7th-edition">1996 AJCC-UICC Regional Lymph Node Classification for Lung Cancer Staging</a></li>