Pathological fracture risk (Mirels classification)
Updates to Article Attributes
Body
was changed:
Mirel classification is a system used to predict the highest risk of pathological fracture among long bones affected by metastases, and is based on site, location, matrix and/or presence of pain.
Classification
- 1 point
- upper limb
- involving <1/3 of bone diameter
- blastic/sclerotic lesion
- mild pain
- 2 points
- lower limb
- involving 1/3-2/3 of bone diameter
- mixed sclerotic/lytic lesion
- moderate pain
- 3 points
- trochanteric region
- involves >2/3 of bone diameter
- lytic lesion
- functional pain
This will give a minimum score of four and a maximum score of 12. A score of ≥8-9≥9 suggests that prophylactic fixation should be performed 1,2. TheFor score 8 lesions, treatment is based on clinical judgement and for lower scores clinical management and radiotherapy is suggested. The overall sensitivity of the Mirel classification predicting fracture is ~90% but specificity is only 35% (meaning there will be unnecessary fixations) leading to debate about its usefulness 1,4.
See also:
-<p><strong>Mirel classification</strong> is a system used to predict the highest risk of <a href="/articles/pathological-fracture">pathological fracture</a> among bones affected by <a href="/articles/skeletal-metastasis-1">metastases</a>, and is based on site, location, matrix and/or presence of pain. </p><h4>Classification</h4><ul>- +<p><strong>Mirel classification</strong> is a system used to predict the highest risk of <a href="/articles/pathological-fracture">pathological fracture</a> among long bones affected by <a href="/articles/skeletal-metastasis-1">metastases</a>, and is based on site, location, matrix and/or presence of pain. </p><h4>Classification</h4><ul>
-</ul><p>This will give a minimum score of four and a maximum score of 12. A score of ≥8-9 suggests that prophylactic fixation should be performed <sup>1,2</sup>. The overall sensitivity of the Mirel classification predicting fracture is ~90% but specificity is only 35% (meaning there will be unnecessary fixations) leading to debate about its usefulness <sup>1,4</sup>.</p><ul></ul>- +</ul><p>This will give a minimum score of four and a maximum score of 12. A score of ≥9 suggests that prophylactic fixation should be performed <sup>1,2</sup>. For score 8 lesions, treatment is based on clinical judgement and for lower scores clinical management and radiotherapy is suggested. The overall sensitivity of the Mirel classification predicting fracture is ~90% but specificity is only 35% (meaning there will be unnecessary fixations) leading to debate about its usefulness <sup>1,4</sup>.</p><h4>See also: </h4><ul><li><a href="/articles/pathological-fracture-risk-harrington-criteria-1">Harrington criteria</a></li></ul>
Unable to process the form. Check for errors and try again.