Pericardial cyst

Changed by Yuranga Weerakkody, 23 Oct 2015

Updates to Article Attributes

Body was changed:

Pericardial cysts are uncommon benign congenital anomaly of the anterior and middle mediastinum. 

Clinical presentation

In most patients are asymptomatic and discovered incidentally although occasionally patients may present with chest pain and dyspnoea. 

Pathology

They are thought to often result from aberrations in the formation of coelomic cavities. They can occur as sequelae of previous pericarditis. The cyst wall is composed of connective tissue and a single layer of mesothelial cells, and usually contains clear fluid. 

Location

They are preferentially found in the right anterior cardiophrenic angle, but can be found almost anywhere adjacent to the heart. They occur more commonly on the right side (right cardio-phrenic angle being the commonest location).

Radiographic features

Plain film: chest radiograph

Typically seen as a mass (added density) at the cardiophrenic sulcus. They can be of different shapes and are not always round. May change in shape and size with inspiration and position.

CT

Usually appears as a well-defined, non-enhancing, low (water) attenuating, rounded mass next to the pericardium. 

MRI

Morphology again can be variable. Internal septations may be present. Signal characteristic are those of fluid and include 4:

  • T1: typically low signal (occasionally can be high signal in contains proteinaceous material)
  • T2: high signal
  • T1 C+ (Gd): no enhancement

Treatment and prognosis

They are benign lesions. Surgical resection or aspiration may be an aspiration for symptomatic selected cases 6-7.

Differential diagnosis

As general differential on cross sectional imaging

On a chest radiograph also consider:

  • -</ul><h4>Differential diagnosis</h4><p>As general differential on cross sectional imaging</p><ul><li>see: <a href="/articles/cystic-mediastinal-masses">cystic mediastinal masses</a>
  • +</ul><h4>Treatment and prognosis</h4><p>They are benign lesions. Surgical resection or aspiration may be an aspiration for symptomatic selected cases<sup> 6-7</sup>.</p><h4>Differential diagnosis</h4><p>As general differential on cross sectional imaging</p><ul><li>see: <a href="/articles/cystic-mediastinal-masses">cystic mediastinal masses</a>
  • -<li><a href="/articles/morgagnis-hernia-1">Morgagni hernia</a></li>
  • +<li><a href="/articles/morgagni-hernia-2">Morgagni hernia</a></li>

References changed:

  • 6. Butz T, Faber L, Langer C, Wiemer M, Horstkotte D, Piper C. Images in Cardiovascular Medicine. Echocardiography-Guided Percutaneous Aspiration of a Large Pericardial Cyst. Circulation. 2007;116(18):e505-7. <a href="https://doi.org/10.1161/CIRCULATIONAHA.107.711903">doi:10.1161/CIRCULATIONAHA.107.711903</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/17967983">Pubmed</a>
  • 7. Najib M, Chaliki H, Raizada A, Ganji J, Panse P, Click R. Symptomatic Pericardial Cyst: A Case Series. Eur J Echocardiogr. 2011;12(11):E43. <a href="https://doi.org/10.1093/ejechocard/jer160">doi:10.1093/ejechocard/jer160</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/21900299">Pubmed</a>

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