Posterior pituitary bright spot
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The posterior pituitary bright spot (PPBS) is a MRI feature of the normal pituitary gland. It refers to the intrinsically high T1 signal of the posterior pituitary thought to be from the storage of vasopressin, which has a T1-shortening effect 2.
It is important to note that a posterior pituitary bright spot is not identified in all patients, but rather somewhere between 50-100% 1,2.
Radiographic features
MRI
- oval/round high T1 signal, best seen on sagittal images in the posterior aspect of pituitary fossa
- normal measurements (decreasing size with age) 1,2
- long axis: 1.2-8.5 mm
- short axis: 0.4-4.4 mm
Related pathology
Absence of PPBS should prompt the consideration of the following (noting it may be absent in normal patients):
- ectopic posterior pituitary
- central diabetes insipidus (correct clinical context obviously required)
- other disease that disrupt the infundibuloneurohypophyseal system, e.g. tumours, infection, inflammation
-<p>The <strong>posterior pituitary bright spot</strong> (<strong>PPBS</strong>) is a MRI feature of the normal <a href="/articles/pituitary-gland">pituitary gland</a>. It refers to the intrinsically high T1 signal of the posterior pituitary thought to be from the storage of vasopressin, which has a T1-shortening effect <sup>2</sup>.</p><p>It is important to note that a posterior pituitary bright spot is not identified in all patients, but rather somewhere between 50-100% <sup>1,2</sup>. </p><h4>Radiographic features</h4><h5>MRI</h5><ul>- +<p>The <strong>posterior pituitary bright spot</strong> (<strong>PPBS</strong>) is a MRI feature of the normal <a href="/articles/pituitary-gland">pituitary gland</a>. It refers to the intrinsically high T1 signal of the <a title="Posterior pituitary" href="/articles/posterior-pituitary">posterior pituitary</a> thought to be from the storage of vasopressin, which has a T1-shortening effect <sup>2</sup>.</p><p>It is important to note that a posterior pituitary bright spot is not identified in all patients, but rather somewhere between 50-100% <sup>1,2</sup>. </p><h4>Radiographic features</h4><h5>MRI</h5><ul>
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