Citation, DOI, disclosures and article data
Citation:
Gaillard F, Snowball sign (Susac syndrome). Reference article, Radiopaedia.org (Accessed on 15 Jan 2025) https://doi.org/10.53347/rID-169287
Disclosures:
At the time the article was created Frank Gaillard had the following disclosures:
- Biogen Australia Pty Ltd, Investigator-Initiated Research Grant for CAD software in multiple sclerosis: finished Oct 2021 (past)
These were assessed during peer review and were determined to
not be relevant to the changes that were made.
View Frank Gaillard's current disclosures
Disclosures:
At the time the article was last revised Frank Gaillard had the following disclosures:
- Biogen Australia Pty Ltd, Investigator-Initiated Research Grant for CAD software in multiple sclerosis: finished Oct 2021 (past)
These were assessed during peer review and were determined to
not be relevant to the changes that were made.
View Frank Gaillard's current disclosures
The snowball sign refers to the appearance of the corpus callosum on FLAIR and T2 weighted sequences in patients with Susac syndrome.
Within the substance of the body and splenium of the corpus callosum, best seen on sagittal images, are spherical well-demarcated high-signal regions 1,2.
This appearance is useful in distinguishing Susac syndrome from corpus callosal involvement in multiple sclerosis, where the lesions tend to preferentially involve the callososeptal interface and extend up into the callosal substance (this is the midline equivalent of Dawson's fingers).
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