Systemic lupus erythematosus (thoracic manifestations)
Updates to Article Attributes
Body
was changed:
Thoracic manifestations of systemic lupus erythematosus can be variable.
Pathology
Pleuropulmonary manifestations
- pleuritis: considered one of the commons of thoracic manifestations 2
- acute lupus pneumonitis
- diaphragmatic dysfunction and shrinking lung syndrome
- cavitating pulmonary nodules
- pulmonary hypertension
- pulmonary vasculitis
- pulmonary embolism (often due to circulating anticardiolipin antibodies)
- pulmonary haemorrhage / alveolar haemorrhage (reflecting diffuse endothelial injury)
-
chronic interstitial pneumonitis: may complicate 3-13% of patients
- interlobular septal thickening 6
- pulmonary fibrosis associated with this can occur but is rare 1
- parenchymal bands
- subpleural bands
- bronchiectasis
- bronchial wall thickening
- pleural thickening
- bronchiolitis obliterans (with or without organising pneumonia)
- opportunistic pulmonary infection or drug toxicity from immunosuppressive therapy
Cardiac complications
- pancarditis
- Libman-Sacks endocarditis: sterile vegetations on the mitral and aortic valves (rare)
See also
-<a href="/articles/chronic-interstitial-pneumonitis">chronic interstitial pneumonitis</a>: may complicate 3-13% of patients<ul><li>- +<a href="/articles/chronic-interstitial-pneumonitis">chronic interstitial pneumonitis</a>: may complicate 3-13% of patients<ul>
- +<li>
- +<a title="Interlobular septal thickening" href="/articles/interlobular-septal-thickening">interlobular septal thickening</a><sup> 6</sup>
- +</li>
- +<li>
-</li></ul>- +</li>
- +<li><a title="Pulmonary parenchymal bands" href="/articles/pulmonary-parenchymal-bands">parenchymal bands</a></li>
- +<li><a title="subpleural bands" href="/articles/subpleural-bands">subpleural bands</a></li>
- +<li><a title="Bronchiectasis" href="/articles/bronchiectasis">bronchiectasis</a></li>
- +<li><a title="Bronchial wall thickening" href="/articles/bronchial-wall-thickening">bronchial wall thickening</a></li>
- +<li><a title="Pleural thickening" href="/articles/pleural-thickening">pleural thickening</a></li>
- +</ul>
References changed:
- 6. Fenlon HM, Doran M, Sant SM, Breatnach E. High-resolution chest CT in systemic lupus erythematosus. AJR. American journal of roentgenology. 166 (2): 301-7. <a href="https://doi.org/10.2214/ajr.166.2.8553934">doi:10.2214/ajr.166.2.8553934</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/8553934">Pubmed</a> <span class="ref_v4"></span>