Terminal duct lobular unit
Updates to Article Attributes
Each breast lobe is drained by a collecting duct terminating in the nipple. The collecting duct has several branches, which end in a terminal ductal-lobular unit (TDLU), the basic functional and histopathological unit of the breast. The TDLU is composed of a small segment of terminal duct and a cluster of ductules, which are the effective secretory units. The functional structures are surrounded by specializedspecialised connective tissue. A normal terminal ductal lobular-lobular unit ranges from 1-4 mm.
The TDLU consists of the:
- extralobular terminal duct
- intralobular terminal duct
- lobule (functional unit of the breast)
Function
This is the most important structure in the breast. It is the galndularglandular unit that produces milk.
Related pathology
It is postulated that most cancers and benign lesions arise in the terminal duct either inside or just proximal to the lobule. For example:
-<p>Each breast lobe is drained by a collecting duct terminating in the nipple. The collecting duct has several branches, which end in a <strong>terminal ductal-lobular unit (TDLU)</strong>, the basic functional and histopathological unit of the breast. The TDLU is composed of a small segment of terminal duct and a cluster of ductules, which are the effective secretory units. The functional structures are surrounded by specialized connective tissue. A normal terminal ductal lobular unit ranges from 1-4 mm.</p><p>The TDLU consists of the:</p><ul>- +<p>Each breast lobe is drained by a collecting duct terminating in the nipple. The collecting duct has several branches, which end in a <strong>terminal ductal-lobular unit (TDLU)</strong>, the basic functional and histopathological unit of the breast. The TDLU is composed of a small segment of terminal duct and a cluster of ductules, which are the effective secretory units. The functional structures are surrounded by specialised connective tissue. A normal terminal ductal-lobular unit ranges from 1-4 mm.</p><p>The TDLU consists of the:</p><ul>
-</ul><h4>Function</h4><p>This is the most important structure in the breast. It is the galndular unit that produces milk.</p><h4>Related pathology</h4><p>It is postulated that most cancers and benign lesions arise in the terminal duct either inside or just proximal to the lobule. For example:</p><ul>- +</ul><h4>Function</h4><p>This is the most important structure in the breast. It is the glandular unit that produces milk.</p><h4>Related pathology</h4><p>It is postulated that most cancers and benign lesions arise in the terminal duct either inside or just proximal to the lobule. For example:</p><ul>
-<li><a href="/articles/fibroadenoma-of-the-breast-1">fibroadenoma of the breast</a></li>- +<li><a href="/articles/fibroadenoma-breast">fibroadenoma of the breast</a></li>
-<li><a href="/articles/adenosis-of-the-breast">adenosis of the breast </a></li>- +<li><a href="/articles/adenosis-of-the-breast">adenosis of the breast </a></li>
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