The 5th Edition of the World Health Organisation classification of Central Nervous System tumours was published online in late 2021 and included many changes both to the overall schema of the classification of many common conditions as well many changes to specific diagnoses. Additionally, a number of new entities have been recognised.
Many editors and contributors, first and foremost two Francesci (Francesco Buemi and Francesco (Frank) Gaillard), reviewed and updated over 100 articles, wrote over a dozen new articles and just as importantly deleted or merged many others.