Acute CPPD crystal arthritis (formerly pseudogout)

Case contributed by Rob Foley
Diagnosis certain

Presentation

Acute presentation with a swollen right knee, warm and painful to touch, the patient unable to weight bear. CRP is 120? infection.

Patient Data

Age: 80 years
Gender: Female

Large knee joint effusion. Severe degenerative change in the patellofemoral joint. Mild medial and lateral compartment degeneration with faint chondrocalcinosis. No specific features of infection although radiography is insensitive to this.  

Marked patellofemoral degeneration in comparison to the tibiofemoral compartments raises the possibility of CPPD for joint fluid analysis.

Case Discussion

The joint was aspirated and the fluid was sent for analysis which demonstrated pyrophosphate crystals on examination under polarized light.

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