Air-tissue interface sign - breast

Case contributed by Mohammad Taghi Niknejad
Diagnosis certain

Presentation

Baseline screening mammography.

Patient Data

Age: 40 years
Gender: Female
mammography

An oval, well-defined mass with an air-tissue interface sign is seen in the lower inner quadrant of the right breast.

Foci of calcifications with a benign appearance are scattered in the right breast.

Additionally, a few small masses with partially obscured margins, without internal calcification and surrounding parenchymal distortion, are observed in the right breast, which appears more consistent with benign breast lesions.

Case Discussion

This case demonstrates a typical air-tissue interface sign on mammography that helps to distinguish a dermal lesion from the intra-mammary mass. Due to the presence of air near a part of the margin, the skin-based lesion's border is pretty sharp, and a narrow, lucent rim can be seen around the lesion, called the air-tissue interface.

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