Amyotrophic lateral sclerosis

Case contributed by Heba Abdelmonem
Diagnosis almost certain

Presentation

Gradual onset progressive quadriparesis with hypereflexia, hypertonia and tongue fasciculation.

Patient Data

Age: 50 years
Gender: Female
mri

Abnormally increased T2 / FLAIR signals in the posterior limb of both internal capsules, extending superiorly to the subcortical white matter of motor cortex and inferiorly along the corticospinal tracts.

Case Discussion

MRI findings and clinical data is highly characteristic for Amyotrophic lateral sclerosis.

Amyotrophic lateral sclerosis (ALS) is a motor neuron disease characterized by progressive degeneration of upper motor neurons (UMN) and lower motor neurons (LMN).

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