As of the latest update, Google Chrome and Microsoft Edge have made a breaking change to how file uploads are handled. Once your system installs this update, you will not be able to upload new images. Please use another browser until we can get it fixed.

Atypical teratoid rhabdoid tumor

Case contributed by Dr Hani Salam

Presentation

Infant with a mass on CT (not shown) for further evaluation

Patient Data

Age: 4 months
Gender: Female

Left lateral intraventricular mass lesion.

The patient went on to have a craniotomy and debulking of the tumour. 

Histology

Frozen section diagnosis: Left lateral ventricular tumor: Malignant neoplasm, differential between choroid plexus carcinoma and atypical teratoid rhabdoid tumor and anaplastic ependymoma.

Immunohistochemistry: CTK+, EMA+, GFAP+, NFP-, VIMENTIN+, SYNAPTOPHYSIN+, CD56 focal, BAF-47 absent, SMA+

Electron Microscopy: EM07-513

FINAL DIAGNOSIS: Atypical teratoid / rhabdoid tumour (AT/RT)

Case Discussion

This very aggressive tumor with extension into the ventricles was shown to be an atypical teratoid / rhabdoid tumor (AT/RT), which more frequently occur in the posterior fossa. A reasonable differential on imaging in this age group is of a choroid plexus carcinoma. 

PlayAdd to Share

Case information

rID: 10712
Published: 11th Sep 2010
Last edited: 13th Aug 2019
Inclusion in quiz mode: Included

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.