Congenital cerebral toxoplasmosis

Case contributed by Nick Tarasov
Diagnosis probable

Presentation

Non-specific headaches. CT (not shown) revealed brain calcifications. Patient was treated surgically for vision problems in early childhood.

Patient Data

Age: 35 years
Gender: Female

There are multiple subcortical and subependymal calcifications in the parietal, occipital, and temporal lobes without perifocal brain changes.

The right ventricle is enlarged, and there is no obstruction of the right foramen of Magendie.

There are a few foci of white matter gliosis in frontal lobes consistent with small vessel disease.

Mild cerebral atrophy.

Case Discussion

Patient's history revealed a fact of her mother, being pregnant, contact with an infected cat.

In childhood patient suffered from chorioretinitis and strabismus, treated surgically.

Subependymal calcifications and enlarged ventricle are possible signs of tuberous sclerosis complex, but there are no clinical symptoms of TS.

This case shows an unusual pattern of brain calcifications in a patient with a congenital cerebral toxoplasmosis.

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