Extramedullary haematopoiesis - presacral mass
Updates to Study Attributes
Pelvic MRI shows a large, inhomogeneous, multilobulated, presacral mass, depicting markedly low SIsignal in both T1WIT1-weighted and T2WIT2-weighted images. Also, visualized skeleton shows markedly low SIsignal in both T1WIT1-weighted and T2WIT2-weighted images.
Updates to Case Attributes
In this patient, a known case of thalassemia major, the lobulated presacral mass 3 arisingarising from sacral bone appears to be due to extramedullary hematopoiesis. It typically occurs in paraspinal location1 (as in this case). Lesion showedshows attenuation in CT greater than that of a skeletal muscle, and Low SI on T1WImarkedly low signals in MRI in both T1-weighted and T2WI owingT2-weighted images, owing to massive iron deposition 1, a sequel of repeated blood transfusions.
In the differential diagnosis of soft-tissue retroperitoneal masses, the low signal intensity on T2- weighted images is in favor of extramedullary hematopoiesis 2.
Very Low T1WI and T2WI SI in visualized skeleton was also consequence massive bone marrow iron deposition.
-<p>In this patient, a known case of thalassemia major, the lobulated presacral mass <sup>3</sup> arising from sacral bone appears to be due to <a title="extramedullary hematopoiesis" href="/articles/extramedullary-haematopoiesis">extramedullary hematopoiesis</a>. It typically occurs in paraspinal location<sup>1</sup> (as in this case). Lesion showed attenuation greater than a skeletal muscle, and Low SI on T1WI and T2WI owing to massive iron deposition <sup>1</sup>, a sequel of repeated blood transfusions. </p><p>In the differential diagnosis of soft-tissue retroperitoneal masses, the low signal intensity on T2- weighted images is in favor of <a title="extramedullary hematopoiesis" href="/articles/extramedullary-hematopoiesis">extramedullary hematopoiesis</a> <sup>2</sup>.</p><p>Very Low T1WI and T2WI SI in visualized skeleton was also consequence massive bone marrow iron deposition.</p>- +<p>In this patient, a known case of <a title="thalassemia" href="/articles/thalassemia">thalassemia</a> major, the lobulated presacral mass <sup>3 </sup>arising from sacral bone appears to be due to <a href="/articles/extramedullary-haematopoiesis">extramedullary hematopoiesis</a>. It typically occurs in paraspinal location <sup>1</sup> (as in this case). Lesion shows attenuation in CT greater than that of a skeletal muscle, and markedly low signals in MRI in both T1-weighted and T2-weighted images, owing to massive iron deposition <sup>1</sup>, a sequel of repeated blood transfusions. </p><p>In the differential diagnosis of soft-tissue retroperitoneal masses, the low signal intensity on T2- weighted images is in favor of <a href="/articles/extramedullary-haematopoiesis">extramedullary hematopoiesis</a> <sup>2</sup>.</p><p>Very Low T1WI and T2WI SI in visualized skeleton was also consequence massive bone marrow iron deposition.</p>
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