Focal areas of signal intensity (FASI) - neurofibromatosis type 1

Case contributed by Bouhouche Abdeldjalil , 24 Nov 2023
Diagnosis almost certain
Changed by Joachim Feger, 22 Dec 2023
Disclosures - updated 27 Nov 2023: Nothing to disclose

Updates to Case Attributes

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NeurofibromatosisFocal areas of signal intensity (FASI) - neurofibromatosis type 1 (FASI)
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Imaging findings and clinical presentation are most consistent with focal areas of signal intensity (FASI) in the setting of NF1.

Focal areas of signal intensity (FASI), also known as focal abnormal signal intensity or unidentified bright objects (UBO) are the most common central nervous system abnormalities in neurofibromatosis type 1 (NF1). They most commonly occur in the basal ganglia (often globus pallidus), brainstem, thalamus, cerebellum, and hippocampus. They are not associated with focal neurological deficits and tend to resolve by early adulthood.

  • -<p>Imaging findings and clinical presentation are most consistent with focal areas of signal intensity (FASI) in the setting of NF1.</p><p>Focal areas of signal intensity (FASI), also known as focal abnormal signal intensity or unidentified bright objects (UBO) are the most common central nervous system abnormalities in neurofibromatosis type 1 (NF1). They most commonly occur in the basal ganglia (often globus pallidus), brainstem, thalamus, cerebellum, and hippocampus. They are not associated with focal neurological deficits and tend to resolve by early adulthood.</p>
  • +<p>Imaging findings and clinical presentation are most consistent with <a href="/articles/focal-areas-of-signal-intensity-brain-1" title="Focal areas of signal intensity (FASI)">focal areas of signal intensity (FASI)</a> in the setting of NF1.</p><p>Focal areas of signal intensity (FASI), also known as focal abnormal signal intensity or unidentified bright objects (UBO) are the most common central nervous system abnormalities in neurofibromatosis type 1 (NF1). They most commonly occur in the basal ganglia (often globus pallidus), brainstem, thalamus, cerebellum, and hippocampus. They are not associated with focal neurological deficits and tend to resolve by early adulthood.</p>

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Neurofibromatosis type 1 (FASI)
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Focal areas of signal intensity (FASI) - neurofibromatosis type 1
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