Granulomatous hypophysitis (Tubercular)

Case contributed by Keshaw Kumar
Diagnosis almost certain

Presentation

Headache and fever

Patient Data

Age: 15 years
Gender: Male

Few small lytic areas in the basisphenoid/dorsum sellae.

The pituitary stalk appears mildly bulky.

The brain is otherwise unremarkable.

CEMRI Brain

mri

Homogeneously enhancing mildly bulky pituitary gland and pituitary stalk with normal size sella. There is the erosion and heterogenous enhancement of the clivus/dorsum sellae/basisphenoid associated with thick dural enhancement along the clivus. Edema noted in bilateral optic tracts.

Small mucosal polyp in the sphenoid sinus.

Mild hypertrophy of adenoid.

Impression: Overall imaging findings are in favor of granulomatous hypophysitis

Case Discussion

The CSF study was done and the results are as follows-

Total leukocyte count: 220 cells/cumm.

Differential leukocyte count:

Neutrophils 10%

Lymphocytes: 90%

No immature / abnormal cells were seen.

RBC count: few

Glucose: 20 mg/dl (decreased).

Protein: 279 mg/dl (increased).

Chloride: 115 mmol/L (dereduced

---- The overall clinical history, imaging findings, and CSF study are in favor of Tubercular granulomatous hypophysitis.

Co-authors:

Dr. Mukund prasad, Mch (Neurosurgery).

Dr. Saket ballabh, DMRD, DNB (Radiodiagnosis).

Dr. Sanaullah mudassir, DM (Neuro medicine)

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.