Lepidic-predominant adenocarcinoma of the lung

Case contributed by Ammar Ashraf
Diagnosis certain

Presentation

Post-menopausal lady with episodic excessive sweating (before sleep) and palpitation for 1 year.

Patient Data

Age: 50 years
Gender: Female

Irregular solid nodule with spiculated margins measuring about 9 x 15 mm seen in the peripheral lateral basal segment of the right lower lobe. No calcification, cavitation or fat component is seen in it. Rest of the lungs are clear. No mediastinal lymphadenopathy, pleural thickening/effusion or pneumothorax is seen. Adrenals are normal. No concerning lytic or sclerotic bony lesions.

Histopathology report of the resected right lower lobe pulmonary nodule.

Case Discussion

  • Imaging features are suggestive of a malignant pulmonary nodule (likely primary malignancy). Further imaging work up (CT abdomen, mammogram etc) was negative.

  • The patient underwent resection of this pulmonary nodule via video assisted thoracoscopic surgery (VATS) and the histopathology showed lepidic predominant invasive adenocarcinoma.

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