Optic nerve glioma
Gradual loss of vision in the left eye , associated proptosis. No family history of NF1
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There is fusiform mass involving the left optic nerve. The mass is hyperintense on both FLAIR and T2 imaging.
No evidence of abnormal T2 or FLAIR white matter hyperintensities.
This is an example of optic nerve glioma occuring sporadically (not associated with NF1). The differential diagnosis include optic nerve sheath meningioma (if eccentrically located)
- Miller NR. Primary tumours of the optic nerve and its sheath. Eye (Lond).18 (11): 1026-37. doi:doi:10.1038/sj.eye.6701592 - Pubmed citation
- Kornreich L, Blaser S, Schwarz M et-al. Optic pathway glioma: correlation of imaging findings with the presence of neurofibromatosis. AJNR Am J Neuroradiol. 2001;22 (10): 1963-9. AJNR Am J Neuroradiol (full text) - Pubmed citation
- Czyzyk E, Jóźwiak S, Roszkowski M et-al. Optic pathway gliomas in children with and without neurofibromatosis 1. J. Child Neurol. 2003;18 (7): 471-8. Pubmed citation