Solitary fibrous tumor (hemangiopericytoma)

Case contributed by Adam Krajewski
Diagnosis certain

Presentation

Several weeks of word finding difficulty and right-sided weakness.

Patient Data

Age: 60 years
Gender: Female

Lobulated hypercellular hypervascular mass along the left frontal convexity with adjacent vasogenic edema. It causes significant mass effect, rightward midline shift and effacement of the frontal horn of the left lateral ventricle.

In addition to the above dominant lesion, there is an 8 mm enhancing extra-axial nodule along the floor of the anterior cranial fossa adjacent to the right straight gyrus. This incidental nodule is suspected to represent an olfactory groove meningioma.

Case Discussion

The patient underwent a craniotomy for resection of the left frontal tumor. 

Immunohistochemistry

  • STAT6: positive
  • CD34: positive
  • EMA: negative

Diagnosis: solitary fibrous tumor/hemangiopericytoma (grade 3)

Note: at the time of diagnosis this tumor was known as a hemangiopericytoma. Under the 5th Edition (2021) of the WHO classification of CNS tumors, it is now considered a solitary fibrous tumor of the dura. 

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