Thymoma

Case contributed by Abdallah Al Khateeb , 8 Mar 2016
Diagnosis certain
Changed by Henry Knipe, 8 Mar 2016

Updates to Study Attributes

Caption was removed:
Chest CT

Updates to Case Attributes

Body was changed:

HISTOPATHOLOGY REPORT

MICROSCOPIC DESCRIPTION:- Microscopy shows an encapsulated tumor composedThymomas are a common cause of two alternating cytomorphological and histoarchitectural components. The first component contaings neoplastic epithelium forming delicate loose network, and having large polygonal cells with large nuclei, open chromating and prominent central nucleoli, equally admixed with non-neoplastic lymphocytes. The second component exhibits vaguley solid sheets of neoplastic epithelium composed of polygonal medium-sized cells, with smaller round nuclei and prominent nucleoli,with paucity of lymphocytes. Both compoenents show abundance of Hassall's corpuscles. There are areas of extensive tumor necrosis, small cystic space formation and cholesterol clefts. There is no marked nuclear polymorphism or significant mitotic activityanterior mediastinal masses.

DIAGNOSIS:- Corpuscular thymoma, WHO type B3.

  • -<p>HISTOPATHOLOGY REPORT</p><p><br>MICROSCOPIC DESCRIPTION:<br>- Microscopy shows an encapsulated tumor composed of two alternating cytomorphological and histoarchitectural components. <br>The first component contaings neoplastic epithelium forming delicate loose network, and having large polygonal cells with large <br>nuclei, open chromating and prominent central nucleoli, equally admixed with non-neoplastic lymphocytes. The second component exhibits <br>vaguley solid sheets of neoplastic epithelium composed of polygonal medium-sized cells, with smaller round nuclei and prominent nucleoli,<br>with paucity of lymphocytes. Both compoenents show abundance of Hassall's corpuscles. There are areas of extensive tumor necrosis, small cystic <br>space formation and cholesterol clefts. There is no marked nuclear polymorphism or significant mitotic activity.</p><p>DIAGNOSIS:<br>- Corpuscular thymoma, WHO type B3.</p>
  • +<p><a title="Thymomas" href="/articles/thymic-epithelial-tumours">Thymomas</a> are a common cause of <a title="Anterior mediastinal masses" href="/articles/differential-for-an-anterosuperior-mediastinal-mass">anterior mediastinal masses</a>.</p>

Updates to Freetext Attributes

Description was added:

HISTOPATHOLOGY REPORT

MICROSCOPIC DESCRIPTION: Microscopy shows an encapsulated tumor composed of two alternating cytomorphological and histoarchitectural components.  The first component contains neoplastic epithelium forming delicate loose network, and having large polygonal cells with largenuclei, open chromating and prominent central nucleoli, equally admixed with non-neoplastic lymphocytes. The second component exhibits vaguely solid sheets of neoplastic epithelium composed of polygonal medium-sized cells, with smaller round nuclei and prominent nucleoli, with paucity of lymphocytes. Both components show abundance of Hassall's corpuscles. There are areas of extensive tumor necrosis, small cystic space formation and cholesterol clefts. There is no marked nuclear polymorphism or significant mitotic activity.

DIAGNOSIS: Corpuscular thymoma, WHO type B3.

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.