Treated osteogenesis imperfecta (zebra stripe sign)

Case contributed by Jan Frank Gerstenmaier
Diagnosis almost certain

Presentation

This young child has been receiving bisphosphonates for osteogenesis imperfecta.

Patient Data

Age: 2 years
Gender: Female

AP radiograph of lower limbs demonstrates deformed long bones with alternating dense and lucent metaphyseal bands.

Case Discussion

These sclerotic growth recovery lines in the metaphyses are secondary to bisphosphonate therapy.

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