Search results for “multiple sclerosis”

51 results found
Case

Neuromyelitis optica

  Diagnosis certain
Christine Goh
Published 05 Mar 2015
92% complete
MRI
Article

Owl-eyes sign (spinal cord)

The owl-eyes sign, also known as snake-eyes sign or fried-eggs sign, represents bilaterally symmetric circular to ovoid foci of high T2-weighted signals in the anterior horn cells of the spinal cord and is seen on axial MR imaging. The sagittal corollary is a "pencil-like" vertical linear high T...
Article

Spondylodiscitis

Spondylodiscitis, (rare plural: spondylodiscitides) also referred to as discitis-osteomyelitis, is characterized by infection involving the intervertebral disc and adjacent vertebrae. Terminology In adults, the use of the term discitis is generally discouraged as isolated infection of the spin...
Article

Systemic lupus erythematosus (CNS manifestations)

Central nervous system manifestations of systemic lupus erythematosus (CNS lupus), also known as neuropsychiatric systemic lupus erythematosus (NPSLE), describe a very diverse range of neuropsychiatric manifestations that are secondary to systemic lupus erythematosus (SLE) in the central nervous...
Article

Chordoma

Chordomas are uncommon malignant tumors of the axial skeleton that account for 1% of intracranial tumors and 4% of all primary bone tumors.  They originate from embryonic remnants of the primitive notochord (earliest fetal axial skeleton, extending from the Rathke's pouch to the tip of the cocc...
Article

Neuromyelitis optica spectrum disorder

Neuromyelitis optica spectrum disorder (NMOSD) is a severe demyelinating diseases, which in seropositive cases, is caused by an autoantibody to the aquaporin-4 water channel. The classic presentation of NMOSD is with the triad of optic neuritis, longitudinally extensive myelitis, and positive an...
Article

Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL)

Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL) is a systemic genetic disorder affecting the cerebral small vessels, spine and hair follicles. CARASIL is an HTRA1-related cerebral small vessel disease, and thus is closely related to, but dis...
Article

Neurogenic bladder

Neurogenic bladder is a term applied to a dysfunctional urinary bladder that results from any lack of coordination between the central nervous system and the somatic nervous system 1, including injuries to the central or peripheral nerves that control and regulate urination. Injury to the brain,...
Article

Subacute combined degeneration of the cord

Subacute combined degeneration of the cord is caused by vitamin B12 deficiency. Epidemiology Most common in patients older than 40 years and especially older than 60 years 7.  Clinical presentation The clinical presentation of subacute combined degeneration is usually with loss of vibration ...
Article

Hypomyelination with brainstem and spinal cord involvement and leg spasticity

Hypomyelination with brainstem and spinal cord involvement and leg spasticity (HBSL) is a very rare inherited autosomal recessive leukodystrophy characterized mainly by progressive early-onset lower limb-predominant spasticity. Epidemiology HBSL is extremely rare, although the exact incidence ...
Article

Dorsal cord syndrome

Dorsal cord syndrome, also known as posterior spinal cord syndrome, is one of the incomplete cord syndromes resulting from pathology affecting the posterior part of the spinal cord, particularly the dorsal columns and potentially (in larger lesions) the lateral corticospinal tracts 1.  Clinical...
Article

Longitudinally extensive spinal cord lesion

Longitudinally extensive spinal cord lesions (LESCL), also known as longitudinally extensive transverse myelitis (LETM), represent extensive involvement of the spinal cord, with abnormal T2 signal traversing at least three vertebral body segments in length. Differential diagnosis They is a bro...
Article

Spinal hydatid disease

Spinal hydatid disease is an uncommon manifestation of hydatid disease, caused by the larval stage of Echinococcus granulosus, or less commonly E. alveolaris or E. multilocularis, and describes a spectrum of disease involving the spinal cord, the spine, or both. For a general discussion, and fo...
Case

Complications of sickle cell disease

  Diagnosis certain
Niharika Praveen
Published 25 Sep 2023
93% complete
CT X-ray Fluoroscopy
Article

Neurosarcoidosis

Central nervous system involvement by sarcoidosis, also termed neurosarcoidosis, is relatively common among patients with systemic sarcoidosis and has a bewildering variety of manifestations, often making diagnosis difficult.  For a general discussion of the underlying condition, please refer t...
Case

Subacute combined degeneration of the cord

  Diagnosis certain
Ankur Gulati
Published 15 Jun 2021
95% complete
MRI
Article

HTLV-1-associated myelopathy

HTLV-1-associated myelopathy, also known as tropical spastic paraparesis, is primarily seen in Japan, Melanesia and the Caribbean and presents with chronic spastic paraparesis. Terminology This condition has been independently described in Japan (HTLV-1 associated myelopathy) and in the Caribb...
Article

Vertebra plana

Vertebra plana (plural: vertebrae planae), also known as the pancake, silver dollar or coin-on-edge vertebra, is the term given when a vertebral body has lost almost its entire height anteriorly and posteriorly, representing a very advanced compression fracture. Pathology It can occur in a var...
Article

Cervical degenerative spondylosis (grading)

Cervical degenerative disease is extremely common. Cervical spondylosis can be graded using a very old but reliable classification devised by Jonas Kellgren et al 1,2. It is based on findings on a lateral cervical spine radiograph although it can also be applied to MRI evaluation of spine. The ...
Article

Vertebral metastases

Vertebral metastases represent the secondary involvement of the vertebral spine by hematogenously-disseminated metastatic cells. They must be included in any differential diagnosis of a spinal bone lesion in a patient older than 40 years. This article will focus only on the metastasis involving...

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