Search results for “multiple sclerosis”
19 results found
Article
Intramedullary spinal metastasis
Intramedullary spinal metastases are rare, occurring in ~1% of autopsied cancer patients, and are less common than leptomeningeal metastases.
Intramedullary lesions may result from:
growth along the Virchow-Robin spaces
hematogenous dissemination
direct extension from the leptomeninges
Epid...
Article
Syndrome of inappropriate antidiuretic hormone secretion
The syndrome of inappropriate antidiuretic hormone secretion (SIADH or SIAD) (also known as Schwartz-Bartter syndrome) was initially described in patients with lung cancer who developed hyponatremia associated with continued urinary sodium loss. The result is often dilutional hyponatremia in whi...
Article
Intramedullary spinal tumors
Intramedullary spinal tumors are rare, representing 4-10% of all CNS tumors and <10% of all pediatric CNS neoplasms 5. They account for 20% of all intraspinal tumors in adults and 35% of all intraspinal tumors in children 8.
A long duration of symptoms prior to diagnosis is typical.
Pathology
...
Article
Numb chin syndrome
Numb chin syndrome describes a sensory neuropathy occurring in the distribution of either the mental nerve or inferior alveolar nerve. While numb chin syndrome has a multitude of causes, it is considered an ominous entity due to its strong association with heralding advanced malignancy 1.
Clini...
Article
Lymphoma of the spinal cord
Lymphoma of the spinal cord is an uncommon manifestation of lymphoma. Although lymphoma more commonly involves the vertebral body (vertebral body tumors) or epidural compartment, intramedullary lymphoma may rarely occur.
Apparent intramedullary spinal cord lymphoma may often, in fact, represe...
Article
Optic nerve sheath meningioma
Optic nerve meningiomas are benign tumors arising from the arachnoid cap cells of the optic nerve sheath and represent ~20% of all orbital meningiomas, the majority of which are direct extensions from intracranial meningiomas.
These tumors typically appear as masses within the optic nerve, iso...
Article
Optic nerve enlargement
Enlargement of the optic nerves is uncommon. Swelling of the optic nerves has a surprisingly broad differential.
Etiology
neoplastic
optic nerve glioma
optic nerve meningioma
leukemia
orbital lymphoma
metastases
juvenile xanthogranuloma
medulloepithelioma
involvement by retinoblastoma
...
Article
Vertebra plana
Vertebra plana (plural: vertebrae planae), also known as the pancake, silver dollar or coin-on-edge vertebra, is the term given when a vertebral body has lost almost its entire height anteriorly and posteriorly, representing a very advanced compression fracture.
Pathology
It can occur in a var...
Article
Lytic bone metastases
Lytic bone (osteolytic) metastases are distant tumor deposits of a primary tumor within bone characterized by a loss of bone with the destruction of the bone matrix.
Epidemiology
Lytic bone metastases are more common than sclerotic bone metastases.
Diagnosis
The diagnosis is usually establis...
Article
Pheochromocytoma
Pheochromocytomas are an uncommon tumor of the adrenal gland, with characteristic clinical, and to a lesser degree, imaging features. The tumors are said to follow a 10% rule:
~10% are extra-adrenal
~10% are bilateral
~10% are malignant
~10% are found in children
~10% are not associated wit...
Article
Vertebral metastases
Vertebral metastases represent the secondary involvement of the vertebral spine by hematogenously-disseminated metastatic cells. They must be included in any differential diagnosis of a spinal bone lesion in a patient older than 40 years.
This article will focus only on the metastasis involving...
Article
Dysembryoplastic neuroepithelial tumor
Dysembryoplastic neuroepithelial tumors (DNET) are benign (WHO Grade 1) slow growing glioneuronal tumors arising from either cortical or deep grey matter. They are considered part of the heterogeneous group of tumors known as long-term epilepsy-associated tumors (LEATs).
The vast majority of DN...
Article
Renal osteodystrophy
Renal osteodystrophy, also known as uremic osteopathy, is a constellation of musculoskeletal abnormalities that occur in patients with chronic renal failure, due to concurrent and superimposed:
osteomalacia (adults) or rickets (children)
secondary hyperparathyroidism: abnormal calcium and phos...
Article
Intraventricular masses (an approach)
The ventricular system of the brain plays host to a variety of unique tumors, as well as tumors that are more frequently seen elsewhere (e.g. meningiomas). Besides, some intra-axial (parenchymal) masses can be mostly exophytic and thus appear mostly intraventricular. A systematic approach taking...
Article
Giant cell tumor of bone
Giant cell tumors (GCT) of bone are locally aggressive and rarely malignant or metastasizing bony neoplasms, typically found at the end of long bones which is the region around the closed growth plate extending into the epiphysis and to the joint surface 1. They are classified as osteoclastic gi...
Article
Bone metastases
Bone (skeletal) metastases are the third most frequent behind lung and liver metastases 6. They result in significant morbidity in patients with metastatic disease. Although the diagnosis is often straightforward, especially as in many cases there is a well-documented history of metastatic malig...
Article
Renal oncocytoma
Renal oncocytomas are relatively benign renal tumors. The main clinical importance of this lesion is the difficulty in preoperatively distinguishing it from renal cell carcinomas, as epidemiology, presentation, imaging and even histology can be very similar.
Epidemiology
Renal oncocytomas acc...
Article
Chordoma
Chordomas are uncommon malignant tumors of the axial skeleton that account for 1% of intracranial tumors and 4% of all primary bone tumors.
They originate from embryonic remnants of the primitive notochord (earliest fetal axial skeleton, extending from the Rathke's pouch to the tip of the cocc...
Article
Diffuse brainstem glioma (historical)
Diffuse brainstem gliomas or diffuse intrinsic pontine gliomas was a term used to describe infiltrating astrocytomas arising in the brainstem, usually in children. It is no longer recognized as a distinct entity, removed from the 2016 update to the WHO classification of CNS tumors replaced by a ...
Unable to process the form. Check for errors and try again.