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Mantle cell lymphoma

Mantle cell lymphoma (MCL) is a type of non-Hodgkin lymphoma (NHL) and accounts for ~5% of all NHL. It is a malignant neoplasm of virgin B cells that closely resemble normal mantle zone B cells surrounding germinal centers. Epidemiology They occur in older adults (mean age ~60 years), and ther...

Case

Hepatocellular carcinoma

Diagnosis almost certain

Hani M. Al Salam

Published 11 Jan 2013

81% complete

CT X-ray Ultrasound MRI

Article

Splenic pseudocyst

Splenic pseudocysts, also known as secondary splenic cysts, are acquired cystic lesions not delineated by a true epithelial wall. They represent the majority of the splenic cystic lesions, corresponding to approximately 80% of them (cf. splenic epithelial cysts). The main causes are: splenic t...

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Splenic cyst

Splenic epithelial cysts, also known as splenic epidermoid cysts or primary splenic cysts, are unilocular fluid lesions with thin and smooth walls and no enhancement. They represent ~20% of cysts found in the spleen and are usually an innocuous incidental imaging finding. Note that most (~80%) ...

Case

Extramedullary hematopoiesis

Diagnosis certain

Ian Bickle

Published 06 May 2015

95% complete

X-ray CT Annotated image

Article

Splenic biopsy

Percutaneous splenic biopsy, using either ultrasound or CT guidance, is an accurate and reliable method of acquiring splenic tissue for histopathological assessment and has been proposed as an alternative for splenectomy in selected patients. Although the procedure has been historically feared ...

Case

Complications of sickle cell disease

Diagnosis certain

Niharika Praveen

Published 25 Sep 2023

93% complete

CT X-ray Fluoroscopy

Article

Evans syndrome

Evans syndrome is an autoimmune condition with two or more cytopenias, usually caused by autoimmune hemolytic anemia (AIHA) and immune thrombocytopenia (ITP), with or without immune neutropenia. Epidemiology Evans syndrome is considered rare, with defining bicytopenias present in less than 5% ...

Article

Gallbladder lymphoma

Gallbladder lymphoma is exceedingly rare and presents diagnostic challenges due to its imaging characteristics often resembling those of gallbladder adenocarcinoma. Epidemiology Primary lymphomas of the gallbladder are extremely rare, accounting for approximately 0.1-0.2% of all malignant tumo...

Article

Binet staging system for chronic lymphocytic leukemia

The Binet staging system is one of the two staging systems adopted in assessment of chronic lymphocytic leukemia (CLL). It classifies CLL according to the number of lymphoid tissues that are involved (i.e. the spleen and the lymph nodes of the neck, groin, and underarms), as well as the presenc...

Article

Neurolymphomatosis

Neurolymphomatosis is a rare cause of neuropathy due to infiltration of the peripheral nervous system by a hematologic malignancy, in the great majority a B-cell non-Hodgkin lymphoma. It should be differentiated from non-tumor neuropathies associated with lymphoma, such as irradiation, chemothe...

Question

Question 2296

What is the most likely diagnosis in this patient with a pleural malignancy?

Question

Question 2214

A 40-year-old man presents with a 3-month history of erythema nodosum. Based on the chest X-ray, what is the most likely diagnosis?

Question

Question 3089

Which imaging feature is most indicative of Langerhans cell histiocytosis (LCH) in the lungs?

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Question 426

Which of the following bones undergoes fatty marrow conversion first?

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Question 477

Which tumor is the most common underlying cause of patients with autoimmune encephalitis?

Question

Question 478

As a general rule, patients with antibodies causing autoimmune encephalitis (limbic encephalitis) which target intracellular antigens are more likely to...

Question

Question 479

A 55-year-old woman, previously well, presents with 4-month history of rapid decline in cognitive function. She is imaged with an MRI. What is the most likely diagnosis?

Question

Question 2982

Lumbar radiographs in a 65-year-old male with lower back pain reveal an indistinct margin of the superior endplate of L4. Which of the following is most likely to account for this?

Question

Question 1157

Patients with alpha-1-antitrypsin deficiency are at increased risk of which of the following cancers?

Mantle cell lymphoma

Hepatocellular carcinoma

Splenic pseudocyst

Splenic cyst

Extramedullary hematopoiesis

Splenic biopsy

Complications of sickle cell disease

Evans syndrome

Gallbladder lymphoma

Binet staging system for chronic lymphocytic leukemia

Neurolymphomatosis

Question 2296

Question 2214

Question 3089

Question 426

Question 477

Question 478

Question 479

Question 2982

Question 1157

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