Articles

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1,985 results found
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Crizotinib associated interstitial pneumonitis

Crizotinib associated interstitial pneumonitis is a type of drug-induced lung disease precipitated by a tyrosine kinase/anaplastic lymphoma kinase (ALK) inhibitor Crizotinib used in the treatment of certain forms of non-small cell lung cancer that have certain mutations including the ROS1 mutati...
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Ventilator induced lung injury

Ventilator-induced lung injury (VILI) is a type of acute lung injury usually inflicted or aggravated by mechanical ventilation. It may occur during invasive or non-invasive ventilation. Pathology The predominant mechanisms include: alveolar overdistention (volutrauma) / regional lung overdist...
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Thymic hyperplasia

Thymic hyperplasia is a disorder whereby there is hyperplasia of the thymus. Pathology Thymic hyperplasia can be subdivided into two forms:  true thymic hyperplasia lymphoid thymic hyperplasia Both true thymic hyperplasia and lymphoid hyperplasia manifest as diffuse symmetric enlargement of...
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Aortic hiatus

The aortic hiatus is one of the three major apertures through the diaphragm and lies at the level of T12. Strictly speaking, it is not a real aperture in the diaphragm, but an osseoaponeurotic opening between it and the vertebral column.  The hiatus is situated slightly to the left of the midli...
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Pseudo Meigs syndrome

Pseudo Meigs syndrome refers to a clinical syndrome of pleural effusion and ascites associated with an ovarian tumor that is not a fibroma or a fibroma-like tumor. Pathology Entities that have been reported to result in pseudo Meigs syndrome include Krukenberg tumors colon carcinoma metastas...
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Primary pulmonary artery leiomyosarcoma

Primary pulmonary artery leiomyosarcoma is a form of thoracic sarcoma and an extremely rare tumor of the thorax. Epidemiology The reported incidence rate is very low at around  ~0.001-0.03%. Most patients are around 40 and 60 years at time of diagnosis.  Pathology They are a smooth muscle tu...
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Elephant trunk repair

An elephant trunk repair is a type of open repair procedure devised to address combined aneurysms, it is often a two staged procedure wherein the arch repair is facilitated by sternotomy and a second staged procedure is performed via left thoracotomy for the descending or thoracoabdominal aorta....
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Airway pressure release ventilation

Airway pressure release ventilation (APRV) is an alternative mode for mechanical ventilation. It can be adopted as an alternative method for difficult-to-oxygenate patients with acute lung injury (ALI)  / acute respiratory distress syndrome (ARDS). It is usually not recommended in patients who ...
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Ventriculopleural shunt

Ventriculopleural shunting is an alternative option for the diversion of CSF and relief of hydrocephalus. In this technique, the distal catheter is placed in the pleural space. It is an alternative to a ventriculoperitoneal shunt (often considered the next most used alternative). Complications ...
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Polymyositis (pulmonary manifestations)

Lung involvement in polymyositis can have a number of manifestations including those resembling interstitial lung disease. For a general discussion of polymyositis, please refer to the parent article. Radiographic features The lungs may present with a mixture of different fibrotic patterns, e...
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Esophageal leiomyoma

Esophageal leiomyoma is a benign smooth muscle neoplasm of the esophagus. It is the most common benign tumor of the esophagus. Epidemiology It is most frequently presents in young and middle age groups (20-50 years). The overall incidence is around 8-43 per 10,000 autopsy series 4. Clinical p...
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Hemorrhagic pneumonia

Hemorrhagic pneumonia refers to a descriptive term for pneumonia (infective - inflammatory consolidation of the lung) that is complicated by pulmonary hemorrhage. It can be localized or diffuse to varying degrees depending on the extent of involvement +/- etiological agent. Pathology The preci...
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Preinvasive lesions of the lung

Preinvasive lesions of the lung are those pulmonary lesions that have not yet progressed to malignancy but have the potential to do so. This category includes: squamous dysplasia (SD) of lungs: squamous cell carcinoma in situ (CIS) of lung preinvasive adenocarcinoma of the lung 5,6 atypical a...
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Rapidly progressive pneumoconiosis

Rapidly progressive pneumoconiosis (RPP) is termed a form of pneumoconiosis when the condition shows an increase in chest radiograph profusion by one ILO subcategory in less than 5 years 1. Conditions than can fall into this category include  accelerated silicosis  
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Mesothelioma

Mesothelioma, also known as malignant mesothelioma, is an aggressive malignant tumor of the mesothelium. Most tumors arise from the pleura, and so this article will focus on pleural mesothelioma. Given the presence of the mesothelium in different parts of the body, mesothelioma can arise in var...
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Pneumonia

The term pneumonia is most commonly used to mean acute infection of the lung parenchyma. Sometimes chronic infections are included. Terminology the term consolidation is often erroneously misinterpreted as a synonym for pneumonia some interstitial lung diseases have been classified as interst...
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Silicosis

Silicosis (plural: silicoses) is a fibrotic pneumoconiosis caused by the inhalation of fine particles of crystalline silicon dioxide (silica). Certain occupations such as mining, quarrying, denim sandblasting 9 and tunneling are associated with silicosis. Terminology The disease occurs in two ...
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Primary pleural lymphoma

Primary pleural lymphoma is extremely rare, especially in immunocompetent patients. Epidemiology Primary pleural lymphoma accounts for <0.5% of all non-Hodgkin lymphoma 2 and ~2.5% of primary chest wall tumors 4.  Pathology Primary pleural lymphoma may be Hodgkin or non-Hodgkin lymphoma with...
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Intravenous drug user

Intravenous drug users (IVDU) are people who inject non-medical and controlled medical drugs (and may have substance use disorder) for non-medical purposes. Frequently injected drugs include heroin, cocaine, prescription opioids and methamphetamine 6.  Terminology More neutral terms such as pe...
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Phrenic nerve palsy

Phrenic nerve palsy (also known as phrenic nerve paresis or paralysis) has many causes and can be caused by lesions anywhere along the course of the phrenic nerve, as it travels from the neck, to pierce the diaphragm adjacent to the pericardium. Epidemiology No single demographic is affected, ...

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