Items tagged “haematology”

8 results found
Article

Hodgkin lymphoma

Hodgkin lymphoma or Hodgkin disease (HD) is a type of lymphoma and accounts for ~1% of all cancers. Hodgkin disease spreads contiguously and predictably along lymphatic pathways and is curable in ~90% of cases, depending on its stage and subtype. Epidemiology There is a bimodal distribution in...
Article

WHO classification of haematolymphoid tumours

The World Health Organisation (WHO) classification of haematolymphoid tumours is the most widely used pathologic classification system for haematopoietic and lymphoid neoplasms. The current revision 1, known as the 5th edition, was published in 2022 and supersedes the 4th edition revised publish...
Article

Haemophilic arthropathy

Haemophilic arthropathy refers to permanent joint disease occurring in haemophilia sufferers as a long-term consequence of repeated haemarthrosis.  Epidemiology Around 50% of patients with haemophilia will develop severe arthropathy. Clinical presentation Presents similarly to osteoarthritis...
Article

Binet staging system for chronic lymphocytic leukaemia

The Binet staging system is one of the two staging systems currently adopted in assessment of chronic lymphocytic leukaemia (CLL). It classifies CLL according to the number of lymphoid tissues that are involved (i.e. the spleen and the lymph nodes of the neck, groin, and underarms), as well as ...
Article

Aplastic anaemia

Aplastic anaemia is a rare haematopoietic stem-cell disorder. The condition results in pancytopenia and hypocellular bone marrow. Most cases are acquired, however, there are unusual inherited forms. Pathology Aplastic anaemia manifests as a marked reduction in the number of pluripotent haemato...
Article

Rai staging system for chronic lymphoid leukaemia

The Rai staging system is one of the two staging systems currently adopted in assessment of chronic lymphocytic leukaemia (CLL). It comprises of stages 0 to IV and classifies chronic lymphocytic leukaemia into low, intermediate and high-risk categories, which correspond with stages 0, I and II,...
Article

Idiopathic hypereosinophilic syndrome

Idiopathic hypereosinophilic syndrome (IHES) is a leukoproliferative disorder and refers to a situation when there is an unexplained prolonged eosinophilia with associated organ system dysfunction.  Pathology Individuals have prolonged raised total leucocyte counts with raised eosinophil count...
Article

Disseminated intravascular coagulation

Disseminated intravascular coagulation (DIC), also known as consumption coagulopathy or defibrination syndrome, refers to a systemic phenomenon of overactivation of coagulation and fibrinolysis resulting in widespread clots forming inside blood vessels. Clinical presentation Patients present w...

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