AIDS-related pulmonary lymphoma
Updates to Article Attributes
Body
was changed:
AIDS related-related pulmonary lymphoma (ARPL) is classified as a distinct form of pulmonary lymphoma. Pulmonary involvement is a common extranodal site in AIDS-related NHL.
Pathology
ARPL is typically a high-grade B-cell non-Hodgkin's lymphoma and the majority of patients have advanced HIV infection, with a mean CD4 count of around 67/mm33.
DiagnositcDiagnostic criteria
According to some publications, the diagnostic criteria for pulmonary involvement requires 2:
- positive HIV status
- histologically proven lymphomatous pulmonary involvement
- absence of mediastinal and/or hilar adenopathy on chest radiography
- absence of extrathoracic lymphoma extension
Radiographic features
CT - HRCT chest
Features can be variable and can include:
- multiple peripheral well-defined nodules of varying sizes
- usually, measure around 1-5 cm in diameter
-
thesereflect dense focal monomorphic cellular infiltrates - considered the commonest
of manifestationsmanifestation 1,4
- centrilobular nodules
- subpleural parenchymal infiltrative changes
- peribronchovascular reticular infiltrative changes 4
- peripheral mass
like-like regions (may have associated cavitation). - interlobular septal thickening
See also
-<p><strong>AIDS related pulmonary lymphoma (ARPL)</strong> is classified as a distinct form of <a href="/articles/pulmonary-lymphoma">pulmonary lymphoma</a>. Pulmonary involvement is a common extranodal site in <a href="/articles/aids-related-nhl">AIDS-related NHL</a>.</p><h4>Pathology</h4><p>ARPL is typically a high-grade B-cell non-Hodgkin's lymphoma and the majority of patients have advanced HIV infection, with a mean CD4 count of around 67 <sup>3</sup>.</p><h5>Diagnositc criteria</h5><p>According to some publications, the diagnostic criteria for pulmonary requires <sup>2</sup>:</p><ul>- +<p><strong>AIDS-related pulmonary lymphoma (ARPL)</strong> is classified as a distinct form of <a href="/articles/pulmonary-lymphoma">pulmonary lymphoma</a>. Pulmonary involvement is a common extranodal site in <a href="/articles/aids-related-nhl">AIDS-related NHL</a>.</p><h4>Pathology</h4><p>ARPL is typically a high-grade B-cell non-Hodgkin's lymphoma and the majority of patients have advanced HIV infection, with a mean CD4 count of around 67/mm<sup>3</sup> <sup>3</sup>.</p><h5>Diagnostic criteria</h5><p>According to some publications, the diagnostic criteria for pulmonary involvement requires <sup>2</sup>:</p><ul>
-<li>usually measure around 1-5 cm in diameter</li>-<li>these reflect dense focal monomorphic cellular infiltrates</li>-<li>considered the commonest of manifestations <sup>1,4</sup>- +<li>usually, measure around 1-5 cm in diameter</li>
- +<li>reflect dense focal monomorphic cellular infiltrates</li>
- +<li>considered the commonest manifestation <sup>1,4</sup>
-<li>peripheral mass like regions (may have associated cavitation).</li>- +<li>peripheral mass-like regions (may have associated cavitation).</li>
-</ul><h4>See also</h4><ul><li><a href="/articles/hivaids-pulmonary-manifestations">pulmonary manifestations of HIV/AIDS</a></li></ul>- +</ul><h4>See also</h4><ul><li><a href="/articles/hivaids-pulmonary-manifestations-1">pulmonary manifestations of HIV/AIDS</a></li></ul>
Sections changed:
Unable to process the form. Check for errors and try again.