Pulmonary lymphoma refers to lymphoma which involves the lung parenchyma.
On this page:
Images:
Pathology
Pulmonary lymphoma can be primary or secondary:
-
primary pulmonary lymphoma is rare and usually of non-Hodgkin type; lung involvement may be accompanied by mediastinal lymph node disease however by definition there is no evidence of extrathoracic dissemination for at least 3 months after the initial diagnosis
low-grade B-cell lymphoma (MALToma) - commonest ~ 80% of primary pulmonary lymphoma
high-grade B-cell lymphoma - most commonly B-cell, occasionally anaplastic and peripheral T-cell types
angiocentric immunoproliferative lesion (lymphomatoid granulomatosis)
-
secondary pulmonary lymphoma: relatively common
Two additional categories have also been described which include 4:
lymphoma in patients with post-transplant lymphoproliferative disorders (PTLD)
AIDS-related pulmonary lymphoma (ARL/ARPL)
Radiographic features
CT
A number of features may be present on HRCT which include:
a mass or mass-like consolidation greater than 1 cm with or without cavitations or bronchograms - most common finding according to one study 2
masses of pleural origin
nodules <1 cm
alveolar or interstitial infiltrates
peribronchial or perivascular thickening with or without atelectasis
hilar or mediastinal lymphadenopathy
See also
pulmonary pseudolymphoma: benign inflammatory lymphocytic infiltrate of the lungs