Bright tree appearance (brain)

Last revised by Rohit Sharma on 15 Jul 2024

The bright tree appearance is a radiological pattern appreciated on MRI brain diffusion-weighted sequences in pediatric patients with severe encephalopathy syndromes. The appearance describes widespread restricted diffusion affecting the subcortical white matter, giving the appearance of multiple dendritic ‘bright tree’ branches 1-10.

The bright tree appearance has been described in several pediatric-onset encephalopathy syndromes, including 1-10:

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