Duct penetrating sign (pancreas)

Changed by Bruno Di Muzio, 23 Aug 2020

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Duct penetrating sign is a radiographic sign that can be useful in differentiating between focal pancreatitis (inflammatory pancreatic mass) from pancreatic carcinoma.

A positive sign is when a mass is penetrated by an unobstructed pancreatic duct; this makes focal pancreatitis the most likely cause rather than pancreatic carcinoma. This sign is best appreciated on MRCP (or ERCP).

The duct-penetrating sign on MRCP is more helpful in differentiating between these two entities than a delayed enhancement pattern on CT or MRI.

  • -<p><strong>Duct penetrating sign</strong> is a radiographic sign that can be useful in differentiating between focal <a title="Pancreatitis - acute" href="/articles/acute-pancreatitis">pancreatitis</a> (inflammatory pancreatic mass) from <a href="/articles/pancreatic-neoplasms">pancreatic carcinoma</a>.</p><p>A positive sign is when a mass is penetrated by an unobstructed <a title="Pancreatic ducts" href="/articles/pancreatic-ducts">pancreatic duct</a>; this makes focal pancreatitis the most likely cause rather than pancreatic carcinoma. This sign is best appreciated on <a title="Magnetic resonance cholangiopancreatography (MRCP)" href="/articles/magnetic-resonance-cholangiopancreatography-mrcp-2">MRCP</a> (or <a title="ERCP" href="/articles/endoscopic-retrograde-cholangiopancreatography">ERCP</a>).</p><p>The duct-penetrating sign on MRCP is more helpful in differentiating between these two entities than a delayed enhancement pattern on CT or MRI.</p>
  • +<p><strong>Duct penetrating sign</strong> is a radiographic sign that can be useful in differentiating between focal <a href="/articles/acute-pancreatitis">pancreatitis</a> (inflammatory pancreatic mass) from <a href="/articles/pancreatic-neoplasms">pancreatic carcinoma</a>.</p><p>A positive sign is when a mass is penetrated by an unobstructed <a href="/articles/pancreatic-ducts">pancreatic duct</a>; this makes focal pancreatitis the most likely cause rather than pancreatic carcinoma. This sign is best appreciated on <a href="/articles/magnetic-resonance-cholangiopancreatography-mrcp-2">MRCP</a> (or <a href="/articles/endoscopic-retrograde-cholangiopancreatography">ERCP</a>).</p><p>The duct-penetrating sign on MRCP is more helpful in differentiating between these two entities than a delayed enhancement pattern on CT or MRI.</p>
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Image 1 MRI (T2 HASTE) ( create )

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