Expanded amnion sign

Last revised by Henry Knipe on 4 Jul 2022

The expanded amnion sign has been described as a poor prognostic sign in early pregnancy, suspicious though not diagnostic of failed early pregnancy. Any visible embryo that is surrounded by an amnion (visible on transvaginal ultrasound) should also have a heartbeat, regardless of crown-rump length. An absent heartbeat in this context is suspicious for early pregnancy loss.

See also

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Cases and figures

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