Gadoterate meglumine
Updates to Article Attributes
Body
was changed:
Gadoterate meglumine (also known by the tradenameDotarem®) is an intravenous extracellular MRI contrast agent.
- cyclic, ionic molecule
- 100% renally excreted
- T1 relaxivity at 1.5 T: 3.4-3.8 L/mmol.S (slightly lower than other extracellular contrast agents)
- concentration: 0.5 mmol/mL
- recommended dosage: 0.1 mmol/kg
It is considered a high-stability agent, and is considered a good choice for patients with lower GFRs (see: nephrogenic systemic fibrosis)
It is also licensed in Europe and Australia for intra-articular use, when it is sold in prefilled syringes as Artirem®, which is chemically identical to Dotarem®. It is not licensed for this use in North America.
Indications
- abdominal or pelvic mass
- HCC screening or evaluation
- evaluation of hepatic haemangioma
- cardiac MRI
- mediastinal MRI
-<a title="T1 relaxivity" href="/articles/t1-relaxivity">T1 relaxivity</a> at 1.5 T: 3.4-3.8 L/mmol.S (slightly lower than other extracellular contrast agents)</li>- +<a href="/articles/t1-relaxivity">T1 relaxivity</a> at 1.5 T: 3.4-3.8 L/mmol.S (slightly lower than other extracellular contrast agents)</li>
-<li><a title="Cardiac MRI" href="/articles/cardiac-mri">cardiac MRI</a></li>- +<li><a href="/articles/cardiac-mri">cardiac MRI</a></li>
Unable to process the form. Check for errors and try again.