Ground-glass density nodule
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A ground glass density nodule (GGN) is a circumscribed area of increased pulmonary attenuation with preservation of the bronchial and vascular margins. A GGN can be:
- partly solid (part of the ground-glass opacity completely obscures the parenchyma)
- non-solid (no completely obscured areas) - pure ground glass nodules
Although encountered regularly, the incidence of cancer in these nodules has been reported as high as 63% (for partly solid nodules, in one study). Histologically these may represent:
- malignancy
- primary (e.g., bronchoalveolar carcinoma (BAC), adenocarcinoma in situ, minimally invasive adenocarcinoma and invasive adenocarcinoma)
- metastases: occasionally can manifest as ground glass density nodules 6
- atypical adenomatous hyperplasia
- focal interstitial fibrosis
- aspergillosis
- focal pulmonary haemorrhages
See also
-<li>primary (e.g., <a href="/articles/adenocarcinoma-in-situ-minimally-invasive-adenocarcinoma-and-invasive-adenocarcinoma-of-lung">bronchoalveolar carcinoma</a> (BAC), <a href="/articles/adenocarcinoma-in-situ-of-lung">adenocarcinoma in situ</a>, <a href="/articles/minimally-invasive-adenocarcinoma-of-lung">minimally invasive adenocarcinoma</a> and <a href="/articles/invasive-adenocarcinoma-of-lung">invasive adenocarcinoma</a>)</li>- +<li>primary (e.g., <a href="/articles/adenocarcinoma-in-situ-minimally-invasive-adenocarcinoma-and-invasive-adenocarcinoma-of-lung">bronchoalveolar carcinoma</a> (BAC), <a href="/articles/adenocarcinoma-in-situ-of-the-lung">adenocarcinoma in situ</a>, <a href="/articles/minimally-invasive-adenocarcinoma-of-lung">minimally invasive adenocarcinoma</a> and <a href="/articles/invasive-adenocarcinoma-of-lung">invasive adenocarcinoma</a>)</li>
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