Adenocarcinoma in situ of the lung

Adenocarcinoma in situ (AIS) of lung refers to a relatively new entity for a pre-invasive lesion in the lung. This entity partly replaces the noninvasive end of the previous term bronchoalveolar carcinoma. AIS is defined as a localised adenocarcinoma of <3 cm, that exhibits a lepidic pattern with neoplastic cells along the alveolar structures but without stromal, vascular, or pleural invasion 1.

Radiographic features


While AIS is usually seen a pure ground glass nodule or a part-solid lung nodule, there can be is an overlap among the imaging features of AAH, AIS, and invasive adenocarcinoma of lung 1.

Treatment and prognosis

AIS carries an excellent prognosis with reported survival rates following complete resection at 100%.

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Article Information

rID: 22176
System: Chest
Section: Pathology
Tag: cases
Synonyms or Alternate Spellings:
  • Adenocarcinoma in situ (AIS) of lung
  • AIS of lung
  • AIS lung
  • AIS
  • Adenocarcinoma in situ (lung)
  • Adenocarcinoma in situ of lung
  • Adenocarcinoma in situ (AIS) of the lung

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