High-grade glioma
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High-grade glioma is a relatively vague term, and in some ways is best avoided, unless one deliberately wants to be vague / inclusive. It as often (especially in older literature) been used to denote both anaplastic gliomas (WHO grade III) and glioblastomas (WHO grade IV), always including astrocytomas, but variably also including oligodendrogliomas, oligoastrocytomas, and ependymomas.
In more recent times, its meaning has at times narrowed to refer primarily to glioblastomas, but this is far from universally accepted.
As such it is best, when wanting to be precise, to use WHO classification terminology.
-<p><strong>High-grade glioma</strong> is a relatively vague term, and in some ways is best avoided, unless one deliberately wants to be vague / inclusive. It as often (especially in older literature) been used to denote both anaplastic gliomas (<a title="WHO grading system for diffuse astrocytomas" href="/articles/who-grading-system-for-diffuse-astrocytomas">WHO grade III</a>) and glioblastomas (<a title="WHO grading system for diffuse astrocytomas" href="/articles/who-grading-system-for-diffuse-astrocytomas">WHO grade IV</a>), always including <a title="Astrocytomas" href="/articles/astrocytic-tumours">astrocytomas</a>, but variably also including <a title="Oligodendrogliomas" href="/articles/oligodendroglioma">oligodendrogliomas</a>, <a title="Oligoastrocytomas" href="/articles/oligoastrocytoma">oligoastrocytomas</a>, and <a title="Ependymomas" href="/articles/ependymoma">ependymomas</a>.</p><p>In more recent times, its meaning has at times narrowed to refer primarily to <a title="Glioblastomas" href="/articles/glioblastoma">glioblastomas</a>, but this is far from universally accepted.</p><p>As such it is best, when wanting to be precise, to use <a title="WHO Classification of CNS tumours" href="/articles/cns-tumours-classification-who">WHO classification</a> terminology. </p><p> </p>- +<p><strong>High-grade glioma</strong> is a relatively vague term, and in some ways is best avoided, unless one deliberately wants to be vague / inclusive. It as often (especially in older literature) been used to denote both anaplastic gliomas (<a href="/articles/who-grading-system-for-diffuse-astrocytomas">WHO grade III</a>) and glioblastomas (<a href="/articles/who-grading-system-for-diffuse-astrocytomas">WHO grade IV</a>), always including <a href="/articles/astrocytic-tumours">astrocytomas</a>, but variably also including <a href="/articles/oligodendroglioma">oligodendrogliomas</a>, <a href="/articles/oligoastrocytoma">oligoastrocytomas</a>, and <a href="/articles/ependymoma">ependymomas</a>.</p><p>In more recent times, its meaning has at times narrowed to refer primarily to <a href="/articles/glioblastoma">glioblastomas</a>, but this is far from universally accepted.</p><p>As such it is best, when wanting to be precise, to use <a href="/articles/cns-tumours-classification-who">WHO classification</a> terminology. </p><p> </p>
Systems changed:
- Central Nervous System
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