Leukemia (thoracic manifestations)
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Thoracic manifestations of leukaemia can be divided into those related to the disease itself and those associated with its treatment. Leukaemias are haematologic malignancies in which occur a proliferation of haematopoietic cells at an undifferentiated or partially differentiated stage of maturation.
Direct involvement
In the thorax,
-
lymphadenopathy
- the most frequent manifestation of leukaemia
isin thelymphadenopathy, butinvolvement of the lungs, pleura, heart, bones, and soft tissues (e.g. breastthorax - commonly seen in lymphoid leukaemias
-
axillary lymphadenopathy is more common in CLL (~48%)
may also occur6.
- the most frequent manifestation of leukaemia
- pulmonary leukaemic infiltrates
- pulmonary leukostasis
-
myeloid sarcoma
- although the thorax is uncommonly involved, it may occur in the lungs, pleura, mediastinum, chest wall, and breast 6
Treatment-related complications
- superimposed infection
- drug-related pathology
-<p><strong>Thoracic manifestations of leukaemia</strong> can be divided into those related to the disease itself and those associated with its treatment. <a href="/articles/leukaemia">Leukaemias</a> are haematologic malignancies in which occur a proliferation of haematopoietic cells at an undifferentiated or partially differentiated stage of maturation.</p><h6>Direct involvement</h6><p>In the thorax, the most frequent manifestation of leukaemia is <a title="Lymphadenopathy" href="/articles/lymph-node-enlargement">lymphadenopathy</a>, but the involvement of the lungs, pleura, heart, bones, and soft tissues (e.g. breast) may also occur <sup>6</sup>. </p><ul>- +<p><strong>Thoracic manifestations of leukaemia</strong> can be divided into those related to the disease itself and those associated with its treatment. <a href="/articles/leukaemia">Leukaemias</a> are haematologic malignancies in which occur a proliferation of haematopoietic cells at an undifferentiated or partially differentiated stage of maturation.</p><h6>Direct involvement</h6><ul>
- +<li>
- +<a href="/articles/lymph-node-enlargement">lymphadenopathy</a><ul>
- +<li>the most frequent manifestation of leukaemia in the thorax</li>
- +<li>commonly seen in lymphoid leukaemias</li>
- +<li>axillary lymphadenopathy is more common in <a title="Chronic lymphocytic leukaemia" href="/articles/chronic-lymphocytic-leukaemia">CLL</a> (~48%) <sup>6</sup>
- +</li>
- +</ul>
- +</li>
- +<li>
- +<a href="/articles/myeloid-sarcoma-1">myeloid sarcoma</a><ul><li>although the thorax is uncommonly involved, it may occur in the lungs, pleura, mediastinum, chest wall, and breast <sup>6</sup>
- +</li></ul>
- +</li>