Maxillary antral carcinoma

Maxillary antral carcinomas are an uncommon head and neck malignancy. They usually present late despite growing large since it remains confined within the maxillary sinus and produces no symptoms.

Most commonly affects patients aged over 45 years and has a strong male predilection (M:F = 5:1). Maxillary antral carcinomas are more in common in Africa and Asia than in Europe and North America 2

When symptoms occur, they include, unilateral stiffness and obstruction, blood tinged nasal discharge, proptosis, diplopia, pain resembling toothache and enlargement and ulceration of the palate.

The underlying histology of maxillary antral carcinomas are variable 2:


The exact cause of maxillary antral carcinomas but exposure to wood dust along with EBV and HPV infection have been implicated in its pathogenesis 2.

It appears as irregular radiopacity within the sinus, perforating the sinus wall.

It includes a combination of surgery and radiation therapy. Prognosis is extremely poor with a 5-year survival of ~10% 1

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Article Information

rID: 6702
System: Head & Neck
Section: Pathology
Tags: refs, cases
Synonyms or Alternate Spellings:

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