Necrosis
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Necrosis (plural: necroses) is defined as unregulated cell death. This is in contrast to apoptosis, which is a form of regulated, or programmed, cell death 1.
Necrosis is the most common type of cell death observed in injury/disease. It occurs when cellular damage is so severe that lysosomal enzymes enter the cytoplasm, causing autodigestion of the cell 1.
The main types of necrosis are:
- coagulative: tissue architecture is preserved
- liquefactive: loss of tissue architecture, formation of liquid/pus
-
caseous: most common with tuberculosis; friable,
structurelessstructure less cell debris - fat necrosis: refers to local areas of fat destruction, commonly encountered in pancreatitis 1
-<p><strong>Necrosis</strong> (plural: necroses) is defined as unregulated cell death. This is in contrast to <a title="Apoptosis" href="/articles/apoptosis">apoptosis</a>, which is a form of regulated, or programmed, cell death <sup>1</sup>. </p><p>Necrosis is the most common type of cell death observed in injury/disease. It occurs when cellular damage is so severe that lysosomal enzymes enter the cytoplasm, causing autodigestion of the cell <sup>1</sup>. </p><p>The main types of necrosis are:</p><ul>-<li>coagulative: tissue architecture is preserved </li>-<li>liquefactive: loss of tissue architecture, formation of liquid/pus</li>-<li>caseous: most common with <a title="Tuberculosis" href="/articles/tuberculosis">tuberculosis</a>; friable, structureless cell debris</li>-<li>fat necrosis: refers to local areas of fat destruction, commonly encountered in <a title="Pancreatitis" href="/articles/pancreatitis">pancreatitis</a> <sup>1</sup>- +<p><strong>Necrosis</strong> (plural: necroses) is defined as unregulated cell death. This is in contrast to <a href="/articles/apoptosis">apoptosis</a>, which is a form of regulated, or programmed, cell death <sup>1</sup>. </p><p>Necrosis is the most common type of cell death observed in injury/disease. It occurs when cellular damage is so severe that lysosomal enzymes enter the cytoplasm, causing autodigestion of the cell <sup>1</sup>. </p><p>The main types of necrosis are:</p><ul>
- +<li>
- +<a title="coagulative" href="/articles/coagulative">coagulative</a>: tissue architecture is preserved </li>
- +<li>
- +<a title="Liquefactive necrosis" href="/articles/liquefactive-necrosis">liquefactive</a>: loss of tissue architecture, formation of liquid/pus</li>
- +<li>
- +<a title="caseous necrosis" href="/articles/caseous-necrosis">caseous</a>: most common with <a href="/articles/tuberculosis">tuberculosis</a>; friable, structure less cell debris</li>
- +<li>
- +<a title="fat necrosis (general)" href="/articles/fat-necrosis-general">fat necrosis</a>: refers to local areas of fat destruction, commonly encountered in <a href="/articles/pancreatitis">pancreatitis</a> <sup>1</sup>
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