Cocaine-induced pneumonitis

Case contributed by Yaïr Glick
Diagnosis almost certain

Presentation

Shortness of breath, desaturation. No fever.

Patient Data

Age: 17 years
Gender: Male
x-ray

Perihilar linear opacities.
Micronodules scattered throughout lungs, with bibasal preponderance.
Subsegmental atelectasis in lung bases.

ct

No embolus in main pulmonary arteries or segmental branches.
Non-enlarged bihilar lymph nodes, probably reactive.
Innumerable diffusely scattered tree-in-bud infiltrates in all lung lobes.
Subsegmental atelectasis in lung bases.

Case Discussion


Shortness of breath and desaturation as low as 89% in room air. Treated with methylprednisolone and inhalations. Echocardiogram normal.
Chest x-rays showed pulmonary micronodules. Pulmonary function tests showed a severe irreversible obstructive lung disease (decrease in FEV1 to 30%) with a disturbance in diffusion.
Urine toxicology came back positive for cocaine and marijuana.
A CTPA done 5 days later showed extensive, diffuse tree-in-bud infiltrates. The pediatric toxicologist was of the opinion that the clinical and radiological picture most probably represented pneumonitis caused by a direct insult to the lungs from cocaine inhalation ("snorting").

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