Presentation
Stiffness, induration, and erythema of the left breast for four weeks without responding to antibiotic therapy.
Patient Data
Obscured mass-like densities with indistinct and irregular margins and fine internal calcifications are seen in the central left breast, along with peri-areolar skin thickening and several ipsilateral axillary enlarged lymph nodes (BI-RADS 5).
Case Discussion
The patient underwent an ultrasound-guided core needle biopsy, and the histopathology evaluation confirmed invasive breast carcinoma of no special type with lymphovascular involvement that suggests inflammatory breast carcinoma, a relatively uncommon but aggressive form of invasive breast carcinoma with a characteristic clinical presentation and unique radiographic appearance.
Clinically and in imaging, inflammatory breast cancer mimics mastitis.
It should be noted that any subtype of primary breast carcinoma can cause inflammatory breast carcinoma, and dermal lymphatic invasion is the key point and pathognomonic for diagnosis. Regarding dermal lymphatic invasion, inflammatory breast cancer is a T4 tumor according to the standard TNM staging classification of breast cancer.
Neo-adjuvant chemotherapy and then left mastectomy with axillary lymphadenectomy were performed. Finally, the patient went to post-surgical chemoradiotherapy.
Unable to process the form. Check for errors and try again.